Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 6992
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163719(3-Cyclohexyl-5-{4-[4-(2-methoxyphenyl)piperazin-1-...)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163721(3-Cyclohexyl-5-{4-[4-(2,3-dichlorophenyl)piperazin...)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163720(3-Cyclohexyl-5-{4-[4-(2-(methylthio)phenyl)piperaz...)
Affinity DataKi:  6nM ΔG°:  -46.9kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163713(5-{4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl}-3-p...)
Affinity DataKi:  9nM ΔG°:  -45.9kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163720(3-Cyclohexyl-5-{4-[4-(2-(methylthio)phenyl)piperaz...)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163717(5-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-...)
Affinity DataKi:  16nM ΔG°:  -44.5kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163714(5-{4-[4-(2-(Methylthio)phenyl)piperazin-1-yl]butyl...)
Affinity DataKi:  17nM ΔG°:  -44.3kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  18nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163719(3-Cyclohexyl-5-{4-[4-(2-methoxyphenyl)piperazin-1-...)
Affinity DataKi:  20nM ΔG°:  -43.9kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163713(5-{4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl}-3-p...)
Affinity DataKi:  27nM ΔG°:  -43.2kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163714(5-{4-[4-(2-(Methylthio)phenyl)piperazin-1-yl]butyl...)
Affinity DataKi:  28nM ΔG°:  -43.1kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163721(3-Cyclohexyl-5-{4-[4-(2,3-dichlorophenyl)piperazin...)
Affinity DataKi:  32nM ΔG°:  -42.8kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163718(3-(2-Chlorophenyl)-5-{4-[4-(2-fluorophenyl)piperaz...)
Affinity DataKi:  37nM ΔG°:  -42.4kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163717(5-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-...)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163716(5-{4-[4-(4-Chlorophenyl)piperazin-1-yl]butyl}-3-ph...)
Affinity DataKi:  79nM ΔG°:  -40.5kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163712(3-Phenyl-5-[4-(4-phenylpiperazin-1-yl)butyl]-4,5-d...)
Affinity DataKi:  79nM ΔG°:  -40.5kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163718(3-(2-Chlorophenyl)-5-{4-[4-(2-fluorophenyl)piperaz...)
Affinity DataKi:  91nM ΔG°:  -40.2kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163712(3-Phenyl-5-[4-(4-phenylpiperazin-1-yl)butyl]-4,5-d...)
Affinity DataKi:  95nM ΔG°:  -40.1kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163715(5-{4-[4-(2-Fluorophenyl)piperazin-1-yl]butyl}-3-ph...)
Affinity DataKi:  100nM ΔG°:  -40.0kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163715(5-{4-[4-(2-Fluorophenyl)piperazin-1-yl]butyl}-3-ph...)
Affinity DataKi:  119nM ΔG°:  -39.5kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Affinity DataKi:  143nM ΔG°:  -39.1kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM163716(5-{4-[4-(4-Chlorophenyl)piperazin-1-yl]butyl}-3-ph...)
Affinity DataKi:  698nM ΔG°:  -35.1kJ/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed