Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50045838
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421256BDBM50421256(CHEMBL2087874)
Affinity DataKi:  0.300nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246164BDBM50246164(N3-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337126BDBM50337126(US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...)
Affinity DataKd:  2nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4552BDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084464BDBM50084464(CHEMBL3426891)
Affinity DataIC50: 5nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084464BDBM50084464(CHEMBL3426891)
Affinity DataIC50: 6nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204587BDBM50204587((S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human LCK using peptide poly[Glu:Tyr] (4:1) substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13216BDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd:  6nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204587BDBM50204587((S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246162BDBM50246162(N3-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084463BDBM50084463(CHEMBL3426880)
Affinity DataIC50: 28nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084454BDBM50084454(CHEMBL3426870)
Affinity DataIC50: 33nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084462BDBM50084462(CHEMBL3426879)
Affinity DataIC50: 34nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 98282BDBM98282(US8481733, 94)
Affinity DataIC50: 35nMAssay Description:Inhibition of ACK1 kinase (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084451BDBM50084451(CHEMBL3426867)
Affinity DataIC50: 48nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084456BDBM50084456(CHEMBL3426872)
Affinity DataIC50: 48nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084457BDBM50084457(CHEMBL3426873)
Affinity DataIC50: 48nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084460BDBM50084460(CHEMBL3426876)
Affinity DataIC50: 53nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084447BDBM50084447(CHEMBL3426861)
Affinity DataIC50: 54nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084455BDBM50084455(CHEMBL3426871)
Affinity DataIC50: 54nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084464BDBM50084464(CHEMBL3426891)
Affinity DataIC50: 56nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084449BDBM50084449(CHEMBL3426865)
Affinity DataIC50: 68nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084452BDBM50084452(CHEMBL3426868)
Affinity DataIC50: 81nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084465BDBM50084465(CHEMBL3426892)
Affinity DataIC50: 82nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084461BDBM50084461(CHEMBL3426877)
Affinity DataIC50: 85nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084453BDBM50084453(CHEMBL3426869)
Affinity DataIC50: 95nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084448BDBM50084448(CHEMBL3426862)
Affinity DataIC50: 99nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084450BDBM50084450(CHEMBL3426866)
Affinity DataIC50: 106nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 98282BDBM98282(US8481733, 94)
Affinity DataIC50: 110nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204589BDBM50204589((S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50: 122nMAssay Description:Inhibition of human LCK using peptide poly[Glu:Tyr] (4:1) substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084464BDBM50084464(CHEMBL3426891)
Affinity DataIC50: 124nMAssay Description:Inhibition of human ROS/ROS1 using KKKSPGEYVNIEFG peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084464BDBM50084464(CHEMBL3426891)
Affinity DataIC50: 136nMAssay Description:Inhibition of human LCK using peptide poly[Glu:Tyr] (4:1) substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421256BDBM50421256(CHEMBL2087874)
Affinity DataKi:  138nMAssay Description:Inhibition of human LCK using peptide poly[Glu:Tyr] (4:1) substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084464BDBM50084464(CHEMBL3426891)
Affinity DataIC50: 143nMAssay Description:Inhibition of human ALK using poly[Glu:Tyr] (4:1) peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084464BDBM50084464(CHEMBL3426891)
Affinity DataIC50: 154nMAssay Description:Inhibition of human CHK1 using KKKVSRSGLYRSPSMPENLNRPR peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084464BDBM50084464(CHEMBL3426891)
Affinity DataIC50: 160nMAssay Description:Inhibition of human FGFR1 using KKKSPGEYVNIEFG peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084446BDBM50084446(CHEMBL3426860)
Affinity DataIC50: 164nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084459BDBM50084459(CHEMBL3426875)
Affinity DataIC50: 169nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084464BDBM50084464(CHEMBL3426891)
Affinity DataIC50: 206nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084458BDBM50084458(CHEMBL3426874)
Affinity DataIC50: 231nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084444BDBM50084444(CHEMBL3426857)
Affinity DataIC50: 299nMAssay Description:Inhibition of human ACK1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of South Florida

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084464BDBM50084464(CHEMBL3426891)
Affinity DataIC50: 438nMAssay Description:Inhibition of human c-Src using poly[Glu:Tyr] (4:1) peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed