Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50045841
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084631(CHEMBL3427203)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of LPS-induced COX1 in human whole blood assessed as reduction in TXB2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50: 7nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50376383(CHEMBL259972)
Affinity DataIC50: 440nMAssay Description:Inhibition of ovine COX-2 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 500nMAssay Description:Inhibition of LPS-induced COX1 in human whole blood assessed as reduction in TXB2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084649(CHEMBL3114664)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084642(CHEMBL3427198)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084631(CHEMBL3427203)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of LPS-induced COX2 in human whole blood assessed as reduction in PGH2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084632(CHEMBL3427204)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084645(CHEMBL3114671)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084643(CHEMBL3427197)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084639(CHEMBL3427202)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084644(CHEMBL3114659)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50084647(CHEMBL3114661)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50: 7.49E+4nMAssay Description:Inhibition of ovine COX-2 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LPS-induced COX2 in human whole blood assessed as reduction in PGH2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed