Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50045537
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067181(CHEMBL3401726)
Affinity DataIC50:  6.40E+3nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067180(CHEMBL3401725)
Affinity DataIC50:  9.80E+3nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067173(CHEMBL3401720)
Affinity DataIC50:  1.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067178(CHEMBL3401723)
Affinity DataIC50:  1.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM39107(MLS000092864 | N-(1H-benzimidazol-2-yl)-4-fluorany...)
Affinity DataIC50:  1.50E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067185(CHEMBL1578123)
Affinity DataIC50:  1.50E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067177(CHEMBL1402439)
Affinity DataIC50:  2.00E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067183(CHEMBL3401728)
Affinity DataIC50:  2.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50275235(CHEMBL486569 | N-(1H-benzo[d]imidazol-2-yl)-4-chlo...)
Affinity DataIC50:  2.50E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM53441(MLS001000876 | N-(1H-benzimidazol-2-yl)-3-chlorany...)
Affinity DataIC50:  2.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50184701(CHEMBL210658 | N-(1H-benzo[d]imidazol-2-yl)-3-nitr...)
Affinity DataIC50:  2.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM95957(MLS000680654 | N-(1H-benzimidazol-2-yl)-4-nitro-be...)
Affinity DataIC50:  3.30E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067179(CHEMBL3401724)
Affinity DataIC50:  3.40E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM38984(MLS000092863 | N-(1H-benzimidazol-2-yl)-2-fluorany...)
Affinity DataIC50:  3.60E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067184(CHEMBL3401729)
Affinity DataIC50:  4.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067176(CHEMBL3401722)
Affinity DataIC50:  4.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067174(CHEMBL3401721)
Affinity DataIC50:  5.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067170(CHEMBL3401716)
Affinity DataIC50:  8.80E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067175(CHEMBL1604245)
Affinity DataIC50:  1.00E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067169(CHEMBL3401715)
Affinity DataIC50:  1.10E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM48291(MLS000566231 | N-(1H-benzimidazol-2-yl)-3-methoxy-...)
Affinity DataIC50:  1.20E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50156074(1,2-bis(3-fluorobenzylidene)hydrazine | CHEMBL3718...)
Affinity DataIC50:  1.36E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067182(CHEMBL3401727)
Affinity DataIC50:  1.50E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067172(CHEMBL3401719)
Affinity DataIC50:  1.60E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM48290(MLS000566310 | N-(1H-benzimidazol-2-yl)benzamide |...)
Affinity DataIC50:  1.60E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067171(CHEMBL3401718)
Affinity DataIC50:  2.10E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed