Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50045537
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067181BDBM50067181(CHEMBL3401726)
Affinity DataIC50: 6.40E+3nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067180BDBM50067180(CHEMBL3401725)
Affinity DataIC50: 9.80E+3nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067173BDBM50067173(CHEMBL3401720)
Affinity DataIC50: 1.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067178BDBM50067178(CHEMBL3401723)
Affinity DataIC50: 1.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 39107BDBM39107(N-1,3-dihydro-2H-benzimidazol-2-ylidene-4-fluorobe...)
Affinity DataIC50: 1.50E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067185BDBM50067185(CHEMBL1578123)
Affinity DataIC50: 1.50E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067177BDBM50067177(CHEMBL1402439)
Affinity DataIC50: 2.00E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067183BDBM50067183(CHEMBL3401728)
Affinity DataIC50: 2.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275235BDBM50275235(N-(1H-benzo[d]imidazol-2-yl)-4-chlorobenzamide | C...)
Affinity DataIC50: 2.50E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184701BDBM50184701(N-(1H-benzo[d]imidazol-2-yl)-3-nitrobenzamide | CH...)
Affinity DataIC50: 2.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 53441BDBM53441(N-(1H-benzimidazol-2-yl)-3-chloranyl-benzamide | N...)
Affinity DataIC50: 2.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 95957BDBM95957(N-1H-benzimidazol-2-yl-4-nitrobenzamide | MLS00068...)
Affinity DataIC50: 3.30E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067179BDBM50067179(CHEMBL3401724)
Affinity DataIC50: 3.40E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 38984BDBM38984(N-1,3-dihydro-2H-benzimidazol-2-ylidene-2-fluorobe...)
Affinity DataIC50: 3.60E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067184BDBM50067184(CHEMBL3401729)
Affinity DataIC50: 4.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067176BDBM50067176(CHEMBL3401722)
Affinity DataIC50: 4.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067174BDBM50067174(CHEMBL3401721)
Affinity DataIC50: 5.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067170BDBM50067170(CHEMBL3401716)
Affinity DataIC50: 8.80E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067175BDBM50067175(CHEMBL1604245)
Affinity DataIC50: 1.00E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067169BDBM50067169(CHEMBL3401715)
Affinity DataIC50: 1.10E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 48291BDBM48291(MLS000566231 | SMR000153406 | cid_853103 | N-(1H-b...)
Affinity DataIC50: 1.20E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156074BDBM50156074(N,N''-Bis-[1-(3-fluoro-phenyl)-meth-(E)-ylidene]-h...)
Affinity DataIC50: 1.36E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067182BDBM50067182(CHEMBL3401727)
Affinity DataIC50: 1.50E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067172BDBM50067172(CHEMBL3401719)
Affinity DataIC50: 1.60E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 48290BDBM48290(cid_2302856 | SMR000153404 | MLS000566310 | N-(1H-...)
Affinity DataIC50: 1.60E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067171BDBM50067171(CHEMBL3401718)
Affinity DataIC50: 2.10E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed