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Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50046380
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007119(4-Amino-3-phenyl-butyric acid | CHEMBL53073)
Affinity DataKi:  9.20E+4nMAssay Description:Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007119(4-Amino-3-phenyl-butyric acid | CHEMBL53073)
Affinity DataKi:  1.77E+5nMAssay Description:Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50007118(4-Amino-3-(5-chloro-thiophen-2-yl)-butyric acid | ...)
Affinity DataIC50:  610nMAssay Description:Binding affinity to GABA-B receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50108998(CHEMBL3600560)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at human recombinant GABA-B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50108997(CGP-71872 | CHEMBL1628548)
Affinity DataKd:  1nMAssay Description:Binding affinity to GABA-B receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50108996(CGP-7930 | CHEMBL1256697)
Affinity DataEC50:  5.37E+3nMAssay Description:Positive allosteric modulator activity at GABA-B receptor (unknown origin) assessed as potentiation of 1 uM GABA-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed