Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50045571
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068462BDBM50068462(CHEMBL3403440 | US9598440, 21)
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068463BDBM50068463(CHEMBL3403441 | US9598440, 20)
Affinity DataIC50: 24nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068465BDBM50068465(CHEMBL3403443 | US9598440, 19)
Affinity DataIC50: 104nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068412BDBM50068412(CHEMBL2018055)
Affinity DataIC50: 170nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068408BDBM50068408(CHEMBL2018064)
Affinity DataIC50: 240nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068403BDBM50068403(CHEMBL2018068)
Affinity DataIC50: 240nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068540BDBM50068540(CHEMBL3403457 | US9598440, 68)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068467BDBM50068467(CHEMBL3403445 | US9598440, 11)
Affinity DataIC50: 410nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068461BDBM50068461(CHEMBL3403439 | US9598440, 83)
Affinity DataIC50: 530nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068417BDBM50068417(CHEMBL3403436 | US9598440, 38)
Affinity DataIC50: 830nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068538BDBM50068538(CHEMBL3403455 | US9598440, 9)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068537BDBM50068537(CHEMBL3403454 | US9598440, 31)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068407BDBM50068407(CHEMBL2018065)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068464BDBM50068464(CHEMBL3403442)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068418BDBM50068418(CHEMBL3403437 | US9598440, 5)
Affinity DataIC50: 2.57E+3nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068466BDBM50068466(CHEMBL3403444)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068410BDBM50068410(CHEMBL3403427)
Affinity DataIC50: 5.19E+3nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068539BDBM50068539(CHEMBL3403456 | US9598440, 26)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068406BDBM50068406(CHEMBL3403429)
Affinity DataIC50: 6.85E+3nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068414BDBM50068414(CHEMBL3403434)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068411BDBM50068411(CHEMBL3403426)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068405BDBM50068405(CHEMBL3403430)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068404BDBM50068404(CHEMBL3403431)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068468BDBM50068468(CHEMBL3403446)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068460BDBM50068460(CHEMBL3403438)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068413BDBM50068413(CHEMBL3403433)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068409BDBM50068409(CHEMBL3403428)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068416BDBM50068416(CHEMBL3403435)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068415BDBM50068415(CHEMBL2018071)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068402BDBM50068402(CHEMBL3403432)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068536BDBM50068536(CHEMBL3403453 | US9598440, 1)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068474BDBM50068474(CHEMBL3403448 | US9598440, 16)
Affinity DataIC50: 2.28E+5nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068476BDBM50068476(CHEMBL3403449 | US9598440, 15)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068483BDBM50068483(CHEMBL3403450)
Affinity DataIC50: 4.03E+5nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068535BDBM50068535(CHEMBL3403452 | US9598440, 17)
Affinity DataIC50: 1.08E+6nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068472BDBM50068472(CHEMBL3403447)
Affinity DataIC50: 1.19E+6nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068534BDBM50068534(CHEMBL3403451 | US9598440, 18)
Affinity DataIC50: 3.01E+6nMAssay Description:Inhibition of N-terminal GST tagged human recombinant full-length IRAK4 expressed in Sf9 insect cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed