Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50045810 Sort by
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50085448(D-Phe-Pro-p-amindinobenzylamine | (S)-1-((R)-2-Ami...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307876((S)-1-((R)-2-amino-2-cyclohexylacetyl)-N-(4-carbam...)
Affinity DataKi:  10nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082643(CHEMBL3423208)
Affinity DataKi:  10nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307872((S)-1-((R)-2-amino-3-methylbutanoyl)-N-(4-carbamim...)
Affinity DataKi:  40nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307856((S)-1-((R)-2-amino-2-cyclohexylacetyl)-N-(3-chloro...)
Affinity DataKi:  40nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307858((S)-1-((R)-2-amino-3-phenylpropanoyl)-N-(3-chlorob...)
Affinity DataKi:  90nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKi:  140nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307869((S)-N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl...)
Affinity DataKi:  220nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307870((S)-1-((R)-2-aminopropanoyl)-N-(4-carbamimidoylben...)
Affinity DataKi:  600nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082521(CHEMBL3423005)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082549(CHEMBL3422995)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082652(CHEMBL3423216)
Affinity DataKi:  1.31E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307866((S)-N-(4-carbamimidoylbenzyl)-1-(2-cyclohexylacety...)
Affinity DataKi:  1.49E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082651(CHEMBL3423215)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307862((S)-N-(4-carbamimidoylbenzyl)-1-(3-methylbutanoyl)...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082650(CHEMBL3423214)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307851((S)-1-((R)-2-amino-3-methylbutanoyl)-N-(3-chlorobe...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307861((S)-1-butyryl-N-(4-carbamimidoylbenzyl)pyrrolidine...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082633(CHEMBL3423013)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307850((S)-1-((R)-2-aminobutanoyl)-N-(3-chlorobenzyl)pyrr...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307860((S)-N-(4-carbamimidoylbenzyl)-1-propionylpyrrolidi...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082648(CHEMBL3423212)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082634(CHEMBL3423012)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082649(CHEMBL3423213)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082635(CHEMBL3423011)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082646(CHEMBL3423211)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307847((S)-N-(3-chlorobenzyl)-1-(3-phenylpropanoyl)pyrrol...)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307849((S)-1-((R)-2-aminopropanoyl)-N-(3-chlorobenzyl)pyr...)
Affinity DataKi:  4.20E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082522(CHEMBL3423001)
Affinity DataKi:  4.50E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082636(CHEMBL3423010)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082640(CHEMBL3423009)
Affinity DataKi:  5.40E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082641(CHEMBL3423008)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082523(CHEMBL3423000)
Affinity DataKi:  7.60E+4nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307844((S)-N-(3-chlorobenzyl)-1-(2-cyclohexylacetyl)pyrro...)
Affinity DataKi:  1.04E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082525(CHEMBL3422999)
Affinity DataKi:  1.36E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307842((S)-N-(3-chlorobenzyl)-1-(4-methylpentanoyl)pyrrol...)
Affinity DataKi:  1.60E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307840((S)-N-(3-chlorobenzyl)-1-(3-methylbutanoyl)pyrroli...)
Affinity DataKi:  1.91E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307838((S)-N-(3-chlorobenzyl)-1-propionylpyrrolidine-2-ca...)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307839((S)-1-butyryl-N-(3-chlorobenzyl)pyrrolidine-2-carb...)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082527(CHEMBL3422998)
Affinity DataKi:  3.70E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082628(CHEMBL3422993)
Affinity DataKi:  3.70E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082629(CHEMBL3422992)
Affinity DataKi:  4.00E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082529(CHEMBL3422997)
Affinity DataKi:  4.30E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082531(CHEMBL3422996)
Affinity DataKi:  5.12E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082588(CHEMBL3422994)
Affinity DataKi:  5.50E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082630(CHEMBL3422991)
Affinity DataKi:  5.80E+5nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082632(CHEMBL3422989)
Affinity DataKi:  1.54E+6nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50082631(CHEMBL3422990)
Affinity DataKi:  1.24E+6nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed