Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50045817
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083317(CHEMBL3423096)
Affinity DataIC50:  2.10E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083267(CHEMBL3423270)
Affinity DataIC50:  3.00E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083318(CHEMBL3423095)
Affinity DataIC50:  4.60E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083334(CHEMBL3423094)
Affinity DataIC50:  4.60E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083316(CHEMBL3423097)
Affinity DataIC50:  5.80E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083313(CHEMBL3423100)
Affinity DataIC50:  6.70E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083315(CHEMBL3423098)
Affinity DataIC50:  7.10E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083265(CHEMBL3423272)
Affinity DataIC50:  1.30E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50156074(1,2-bis(3-fluorobenzylidene)hydrazine | CHEMBL3718...)
Affinity DataIC50:  1.36E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083353(CHEMBL3423092)
Affinity DataIC50:  1.60E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083263(CHEMBL3423274)
Affinity DataIC50:  1.70E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083352(CHEMBL3423093)
Affinity DataIC50:  1.80E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083266(CHEMBL3423271)
Affinity DataIC50:  2.00E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083264(CHEMBL3423273)
Affinity DataIC50:  2.00E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083354(CHEMBL3423091)
Affinity DataIC50:  2.10E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083314(CHEMBL3423099)
Affinity DataIC50:  2.30E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed