Compile Data Set for Download or QSAR
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Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50046154
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  0.100nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096843(CHEMBL3580754)
Affinity DataKi:  0.180nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096838(CHEMBL3580758)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096844(CHEMBL3580753)
Affinity DataKi:  0.320nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096839(CHEMBL3580757)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096845(CHEMBL3580752)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096840(CHEMBL3580756)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096842(CHEMBL3580755)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50063669(CHEMBL3398641)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasma kallikrein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  7nMAssay Description:Inhibition of plasma kallikrein (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096847(CHEMBL3580751)
Affinity DataKi:  12nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096848(CHEMBL3580665)
Affinity DataKi:  19nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >1.60E+3nMAssay Description:Inhibition of urokinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTrypsin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >9.00E+3nMAssay Description:Inhibition of coagulation factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor VII(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of coagulation factor 7a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XII(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of coagulation factor 12a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTissue-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of tPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKallikrein-1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of tissue kallikrein (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >5.40E+4nMAssay Description:Inhibition of APC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor IX(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of coagulation factor 9a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed