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Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50046188
TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098418(CHEMBL3593409)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098418(CHEMBL3593409)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098418(CHEMBL3593409)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098424(CHEMBL3593415)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098424(CHEMBL3593415)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098424(CHEMBL3593415)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098422(CHEMBL3593413)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098422(CHEMBL3593413)
Affinity DataIC50:  43nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098418(CHEMBL3593409)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098422(CHEMBL3593413)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098420(CHEMBL3593411)
Affinity DataIC50:  102nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50:  102nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)
Affinity DataIC50:  166nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098417(CHEMBL3593408)
Affinity DataIC50:  204nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50:  228nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50:  255nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098419(CHEMBL3593410)
Affinity DataIC50:  320nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098417(CHEMBL3593408)
Affinity DataIC50:  332nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098421(CHEMBL3593412)
Affinity DataIC50:  332nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098419(CHEMBL3593410)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098421(CHEMBL3593412)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098418(CHEMBL3593409)
Affinity DataIC50:  341nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098417(CHEMBL3593408)
Affinity DataIC50:  350nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098421(CHEMBL3593412)
Affinity DataIC50:  472nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098415(CHEMBL3593406)
Affinity DataIC50:  544nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098419(CHEMBL3593410)
Affinity DataIC50:  655nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098423(CHEMBL3593414)
Affinity DataIC50:  817nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098415(CHEMBL3593406)
Affinity DataIC50:  825nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098423(CHEMBL3593414)
Affinity DataIC50:  847nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098415(CHEMBL3593406)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098423(CHEMBL3593414)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098424(CHEMBL3593415)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098424(CHEMBL3593415)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed