Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50046340
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106796(CHEMBL3601363)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human His6-tagged SIRT2 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106796(CHEMBL3601363)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human His6-tagged SIRT3 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106871(CHEMBL3601368)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human SIRT5 using CH3CONH-AR-(Nepsilon-succinyl-lysine)-ST-CONH2 as substrate after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106870(CHEMBL3601362)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human His6-tagged SIRT3 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106796(CHEMBL3601363)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human His6 or GST-tagged SIRT1 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106870(CHEMBL3601362)
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of human His6-tagged SIRT2 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106870(CHEMBL3601362)
Affinity DataIC50: 4.99E+4nMAssay Description:Inhibition of human His6 or GST-tagged SIRT1 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50350509(CHEMBL1814814)
Affinity DataIC50: 5.72E+4nMAssay Description:Inhibition of human His6-tagged SIRT3 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 8 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106872(CHEMBL3601366)
Affinity DataIC50: 6.29E+4nMAssay Description:Inhibition of human His6 or GST-tagged SIRT1 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106874(CHEMBL3601364)
Affinity DataIC50: 8.34E+4nMAssay Description:Inhibition of human His6 or GST-tagged SIRT1 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50350509(CHEMBL1814814)
Affinity DataIC50: 8.95E+4nMAssay Description:Inhibition of human His6 or GST-tagged SIRT1 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106875(CHEMBL3601367)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human SIRT5 using CH3CONH-AR-(Nepsilon-succinyl-lysine)-ST-CONH2 as substrate after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106871(CHEMBL3601368)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human His6 or GST-tagged SIRT1 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106876(CHEMBL3601369)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human SIRT5 using CH3CONH-AR-(Nepsilon-succinyl-lysine)-ST-CONH2 as substrate after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106877(CHEMBL3601371)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human SIRT5 using CH3CONH-AR-(Nepsilon-succinyl-lysine)-ST-CONH2 as substrate after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106873(CHEMBL3601365)
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibition of human His6 or GST-tagged SIRT1 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50350509(CHEMBL1814814)
Affinity DataIC50: 1.59E+5nMAssay Description:Inhibition of human His6-tagged SIRT2 using H2N-HK-(Nepsilon-acetyl-lysine)-LM-COOH as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50106871(CHEMBL3601368)
Affinity DataIC50: 2.40E+6nMAssay Description:Inhibition of human SIRT6 using H2N-EALPK-(Nepsilon-myristoyl-lysine)-TGGPQ-CONH2 as substrate after 12 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed