Compile Data Set for Download or QSAR
Report error Found 77 Enz. Inhib. hit(s) with all data for entry = 50046480
LigandChemical structure of BindingDB Monomer ID 50114798BDBM50114798(CHEMBL3608381)
Affinity DataIC50: 8nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114806BDBM50114806(CHEMBL3609752)
Affinity DataIC50: 11nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114837BDBM50114837(CHEMBL3609755)
Affinity DataIC50: 13nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114798BDBM50114798(CHEMBL3608381)
Affinity DataIC50: 18nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114793BDBM50114793(CHEMBL3608392)
Affinity DataIC50: 26nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114796BDBM50114796(CHEMBL3608380)
Affinity DataIC50: 28nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114803BDBM50114803(CHEMBL3608383)
Affinity DataIC50: 28nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114842BDBM50114842(CHEMBL3608390)
Affinity DataIC50: 29nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114800BDBM50114800(CHEMBL3609749)
Affinity DataIC50: 31nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114836BDBM50114836(CHEMBL3608387)
Affinity DataIC50: 36nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114802BDBM50114802(CHEMBL3609750)
Affinity DataIC50: 38nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114845BDBM50114845(CHEMBL3609759)
Affinity DataIC50: 42nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114791BDBM50114791(CHEMBL3609748)
Affinity DataIC50: 45nMAssay Description:Modulation of gamma-secretase in human SKNBE-2 cells assessed as inhibition of intracellular amyloid beta 42 production after 6 hrs by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114839BDBM50114839(CHEMBL3609756)
Affinity DataIC50: 50nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114804BDBM50114804(CHEMBL3609751)
Affinity DataIC50: 56nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114810BDBM50114810(CHEMBL3609754)
Affinity DataIC50: 58nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114844BDBM50114844(CHEMBL3608391)
Affinity DataIC50: 62nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114789BDBM50114789(CHEMBL3609747)
Affinity DataIC50: 67nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing wild type APP751 assessed as inhibition of intracellular amyloid beta 42 production after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114796BDBM50114796(CHEMBL3608380)
Affinity DataIC50: 70nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114805BDBM50114805(CHEMBL3608384)
Affinity DataIC50: 70nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114806BDBM50114806(CHEMBL3609752)
Affinity DataIC50: 73nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114809BDBM50114809(CHEMBL3608386)
Affinity DataIC50: 78nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114807BDBM50114807(CHEMBL3608385)
Affinity DataIC50: 78nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50364033BDBM50364033(CHEMBL1224151)
Affinity DataIC50: 85nMAssay Description:Modulation of gamma-secretase in HEK293 cells expressing Swedish mutant APP assessed as inhibition of intracellular amyloid beta 42 production after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114837BDBM50114837(CHEMBL3609755)
Affinity DataIC50: 100nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114801BDBM50114801(CHEMBL3608382)
Affinity DataIC50: 110nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114803BDBM50114803(CHEMBL3608383)
Affinity DataIC50: 110nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114793BDBM50114793(CHEMBL3608392)
Affinity DataIC50: 120nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114792BDBM50114792(CHEMBL2169963)
Affinity DataIC50: 120nMAssay Description:Modulation of gamma-secretase in HEK293 cells transfected with APPsw-6myc assessed as inhibition of intracellular amyloid beta 42 production after 16...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114800BDBM50114800(CHEMBL3609749)
Affinity DataIC50: 130nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114799BDBM50114799(CHEMBL3608395)
Affinity DataIC50: 145nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114842BDBM50114842(CHEMBL3608390)
Affinity DataIC50: 170nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114790BDBM50114790(CHEMBL2151284)
Affinity DataIC50: 200nMAssay Description:Modulation of gamma-secretase in human SKNBE-2 cells transfected with wild type APP assessed as inhibition of intracellular amyloid beta 42 productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114808BDBM50114808(CHEMBL3609753)
Affinity DataIC50: 210nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114836BDBM50114836(CHEMBL3608387)
Affinity DataIC50: 230nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114843BDBM50114843(CHEMBL3609758)
Affinity DataIC50: 260nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114797BDBM50114797(CHEMBL3608394)
Affinity DataIC50: 270nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114845BDBM50114845(CHEMBL3609759)
Affinity DataIC50: 290nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114840BDBM50114840(CHEMBL3608389)
Affinity DataIC50: 310nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114802BDBM50114802(CHEMBL3609750)
Affinity DataIC50: 310nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114838BDBM50114838(CHEMBL3608388)
Affinity DataIC50: 350nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114839BDBM50114839(CHEMBL3609756)
Affinity DataIC50: 380nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114844BDBM50114844(CHEMBL3608391)
Affinity DataIC50: 380nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114807BDBM50114807(CHEMBL3608385)
Affinity DataIC50: 440nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114810BDBM50114810(CHEMBL3609754)
Affinity DataIC50: 460nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114804BDBM50114804(CHEMBL3609751)
Affinity DataIC50: 500nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114805BDBM50114805(CHEMBL3608384)
Affinity DataIC50: 510nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50364033BDBM50364033(CHEMBL1224151)
Affinity DataIC50: 560nMAssay Description:Modulation of gamma-secretase in HEK293 cells expressing Swedish mutant APP assessed as inhibition of intracellular amyloid beta 40 production after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114809BDBM50114809(CHEMBL3608386)
Affinity DataIC50: 790nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114801BDBM50114801(CHEMBL3608382)
Affinity DataIC50: 800nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
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