Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50046193
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at EPAC2 (unknown origin) assessed as cAMP-induced guanine nucleotide exchange factor activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 6.40E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Displacement of 8-NBD-cAMP from EPAC2 (unknown origin)More data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 9.70E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.08E+4nMAssay Description:Antagonist activity at EPAC1 (unknown origin) assessed as cAMP-induced guanine nucleotide exchange factor activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.08E+4nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.13E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.16E+4nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.19E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.23E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.24E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.51E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.65E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 2.83E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 3.13E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 3.56E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 5.98E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch
Curated by ChEMBL
University of Texas Medical Branch
Curated by ChEMBL
Affinity DataIC50: 6.00E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair