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Report error Found 115 Enz. Inhib. hit(s) with all data for entry = 50046528
TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117300(CHEMBL3613604)
Affinity DataIC50: <1nMAssay Description:Inhibition of AKT1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117301(CHEMBL3613603)
Affinity DataIC50: <1nMAssay Description:Inhibition of AKT1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRAC-alpha serine/threonine-protein kinase(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: <1nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117489(CHEMBL3613598)
Affinity DataIC50: <1nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117489(CHEMBL3613598)
Affinity DataIC50: <1nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: <1nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117503(CHEMBL3613621)
Affinity DataIC50: <1nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117504(CHEMBL3613620)
Affinity DataIC50: <1nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117489(CHEMBL3613598)
Affinity DataIC50: <1nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117370(CHEMBL3613599)
Affinity DataIC50: <1nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117632(CHEMBL3613609)
Affinity DataIC50: <1nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117631(CHEMBL3613610)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117500(CHEMBL3613624)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117315(CHEMBL3613600)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117501(CHEMBL3613623)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117631(CHEMBL3613610)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117635(CHEMBL3613606)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117634(CHEMBL3613607)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117632(CHEMBL3613609)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117504(CHEMBL3613620)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117370(CHEMBL3613599)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117299(CHEMBL3613605)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117503(CHEMBL3613621)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117629(CHEMBL3613612)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117504(CHEMBL3613620)
Affinity DataIC50:  4nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117633(CHEMBL3613608)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117630(CHEMBL3613611)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117301(CHEMBL3613603)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117503(CHEMBL3613621)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117635(CHEMBL3613606)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117300(CHEMBL3613604)
Affinity DataIC50:  7nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117299(CHEMBL3613605)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117303(CHEMBL3613601)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 1(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117632(CHEMBL3613609)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117299(CHEMBL3613605)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of AKT1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117301(CHEMBL3613603)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117502(CHEMBL3613622)
Affinity DataIC50:  8nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117315(CHEMBL3613600)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117627(CHEMBL3613614)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50:  10nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117629(CHEMBL3613612)
Affinity DataIC50:  11nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117302(CHEMBL3613602)
Affinity DataIC50:  12nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117631(CHEMBL3613610)
Affinity DataIC50:  13nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 1(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117489(CHEMBL3613598)
Affinity DataIC50:  16nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117632(CHEMBL3613609)
Affinity DataIC50:  16nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 1(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117303(CHEMBL3613601)
Affinity DataIC50:  18nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 1(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117370(CHEMBL3613599)
Affinity DataIC50:  19nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLIM domain kinase 1(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117503(CHEMBL3613621)
Affinity DataIC50:  20nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50117634(CHEMBL3613607)
Affinity DataIC50:  22nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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