Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50046425
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357312BDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357312BDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111752BDBM50111752(CHEMBL3605107)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111685BDBM50111685(CHEMBL3605102)
Affinity DataIC50: 107nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111755BDBM50111755(CHEMBL3605111)
Affinity DataIC50: 137nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111762BDBM50111762(CHEMBL3605103)
Affinity DataIC50: 176nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111759BDBM50111759(CHEMBL3605106)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111752BDBM50111752(CHEMBL3605107)
Affinity DataIC50: 284nMAssay Description:Inhibition of KDR (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111756BDBM50111756(CHEMBL3605110)
Affinity DataIC50: 292nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111685BDBM50111685(CHEMBL3605102)
Affinity DataIC50: 343nMAssay Description:Inhibition of KDR (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111761BDBM50111761(CHEMBL3605104)
Affinity DataIC50: 387nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111753BDBM50111753(CHEMBL3605113)
Affinity DataIC50: 409nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111754BDBM50111754(CHEMBL3605112)
Affinity DataIC50: 421nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111757BDBM50111757(CHEMBL3605109)
Affinity DataIC50: 454nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111758BDBM50111758(CHEMBL3605108)
Affinity DataIC50: 528nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111760BDBM50111760(CHEMBL3605105)
Affinity DataIC50: 699nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111689BDBM50111689(CHEMBL3605094)
Affinity DataIC50: 768nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111686BDBM50111686(CHEMBL3605101)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111750BDBM50111750(CHEMBL3605097)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111749BDBM50111749(CHEMBL3605098)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111685BDBM50111685(CHEMBL3605102)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111752BDBM50111752(CHEMBL3605107)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111685BDBM50111685(CHEMBL3605102)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111687BDBM50111687(CHEMBL3605100)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111688BDBM50111688(CHEMBL3605095)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111747BDBM50111747(CHEMBL3605093)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111748BDBM50111748(CHEMBL3605099)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111751BDBM50111751(CHEMBL3605096)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111752BDBM50111752(CHEMBL3605107)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111685BDBM50111685(CHEMBL3605102)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111752BDBM50111752(CHEMBL3605107)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed