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Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50046301
TargetLysosomal alpha-glucosidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104748(CHEMBL3594154)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of maltase in rat intestinal mucosa pre-incubated for 40 mins using maltose substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104748(CHEMBL3594154)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of sucrase in rat intestinal mucosa pre-incubated for 40 mins using sucrose substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50356919(CHEMBL1915760)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104745(Ganoderic acid DM)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104745(Ganoderic acid DM)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysosomal alpha-glucosidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104749(CHEMBL3594155)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of maltase in rat intestinal mucosa pre-incubated for 40 mins using maltose substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104764(CHEMBL3594152)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104746(Ganoderic Acid S)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104766(CHEMBL3594158)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104765(CHEMBL3594153)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysosomal alpha-glucosidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibition of maltase in rat intestinal mucosa pre-incubated for 40 mins using maltose substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysosomal alpha-glucosidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104751(CHEMBL3594157)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of maltase in rat intestinal mucosa pre-incubated for 40 mins using maltose substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50356923(CHEMBL1915763)
Affinity DataIC50:  1.68E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104754(CHEMBL3594142)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104751(CHEMBL3594157)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of sucrase in rat intestinal mucosa pre-incubated for 40 mins using sucrose substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104748(CHEMBL3594154)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibition of sucrase in rat intestinal mucosa pre-incubated for 40 mins using sucrose substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104759(CHEMBL3594147)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104753(CHEMBL2203595)
Affinity DataIC50:  2.17E+4nMAssay Description:Inhibition of HMG-CoA reductase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104752(CHEMBL2203597)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of HMG-CoA reductase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104749(CHEMBL3594155)
Affinity DataIC50:  2.25E+4nMAssay Description:Inhibition of sucrase in rat intestinal mucosa pre-incubated for 40 mins using sucrose substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104749(CHEMBL3594155)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104763(CHEMBL3594151)
Affinity DataIC50:  2.64E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104756(CHEMBL3594144)
Affinity DataIC50:  2.66E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM22164((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylca...)
Affinity DataIC50:  3.21E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104761(CHEMBL3594149)
Affinity DataIC50:  3.29E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSucrase-isomaltase, intestinal(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104750(CHEMBL3594156)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of sucrase in rat intestinal mucosa pre-incubated for 40 mins using sucrose substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysosomal alpha-glucosidase(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104750(CHEMBL3594156)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of maltase in rat intestinal mucosa pre-incubated for 40 mins using maltose substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104755(CHEMBL3594143)
Affinity DataIC50:  6.69E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104757(CHEMBL3594145)
Affinity DataIC50:  9.75E+4nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50356920(CHEMBL1915761)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104747(CHEMBL3594160)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104768(CHEMBL3594159)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104767(CHEBI:65945 | GANODERONE A)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104751(CHEMBL3594157)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104762(CHEMBL3594150)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104760(CHEMBL3594148)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104758(CHEMBL3594146)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Pig)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50104750(CHEMBL3594156)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of pig liver microsomes HMG-CoA reductase incubated for 5 mins in using HMG-CoA and NADPH by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed