Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50046706
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127094BDBM50127094(CHEMBL3628383)
Affinity DataIC50: 37nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127089BDBM50127089(CHEMBL3628378)
Affinity DataIC50: 71nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127095BDBM50127095(CHEMBL3628376)
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant ERK2 expressed in Escherichia coli using Omnia peptide S/T17 as substrate measured every 50 seconds for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127090BDBM50127090(CHEMBL3628379)
Affinity DataIC50: 91nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127088BDBM50127088(CHEMBL3628377)
Affinity DataIC50: 149nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127085BDBM50127085(CHEMBL3628373)
Affinity DataIC50: 182nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127082BDBM50127082(CHEMBL3628370)
Affinity DataIC50: 252nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127038BDBM50127038(CHEMBL3628368)
Affinity DataIC50: 280nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127087BDBM50127087(CHEMBL3628375)
Affinity DataIC50: 354nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127036BDBM50127036(CHEMBL3628366)
Affinity DataIC50: 407nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127092BDBM50127092(CHEMBL3628381)
Affinity DataIC50: 416nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127083BDBM50127083(CHEMBL3628371)
Affinity DataIC50: 468nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127091BDBM50127091(CHEMBL3628380)
Affinity DataIC50: 623nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127084BDBM50127084(CHEMBL3628372)
Affinity DataIC50: 634nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127086BDBM50127086(CHEMBL3628374)
Affinity DataIC50: 940nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127081BDBM50127081(CHEMBL3628369)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127093BDBM50127093(CHEMBL3628382)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127037BDBM50127037(CHEMBL3628367)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127031BDBM50127031(CHEMBL3628361)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127028BDBM50127028(CHEMBL3628256)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127027BDBM50127027(CHEMBL3628255)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127033BDBM50127033(CHEMBL3628363)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127029BDBM50127029(CHEMBL3628257)
Affinity DataIC50: 2.16E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127034BDBM50127034(CHEMBL3628364)
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127032BDBM50127032(CHEMBL3628362)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127026BDBM50127026(CHEMBL3628254)
Affinity DataIC50: 2.97E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127035BDBM50127035(CHEMBL3628365)
Affinity DataIC50: 3.19E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127024BDBM50127024(CHEMBL3628252)
Affinity DataIC50: 4.41E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127021BDBM50127021(CHEMBL3628249)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127030BDBM50127030(CHEMBL3628360)
Affinity DataIC50: 7.15E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127025BDBM50127025(CHEMBL3628253)
Affinity DataIC50: 8.97E+4nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127014BDBM50127014(CHEMBL3628248)
Affinity DataKd:  9.70E+4nMAssay Description:Binding affinity to ERK2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127020BDBM50127020(CHEMBL3627726)
Affinity DataKd:  1.25E+5nMAssay Description:Binding affinity to ERK2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127013BDBM50127013(CHEMBL3628247)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127022BDBM50127022(CHEMBL3628250)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127023BDBM50127023(CHEMBL3628251)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205363BDBM50205363(N-benzyl-9H-purin-6-amine | N-benzyladenine | 6-(b...)
Affinity DataKd:  2.47E+5nMAssay Description:Binding affinity to ERK2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127013BDBM50127013(CHEMBL3628247)
Affinity DataKd:  3.19E+5nMAssay Description:Binding affinity to ERK2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127012BDBM50127012(CHEMBL3628246)
Affinity DataKd:  3.43E+5nMAssay Description:Binding affinity to ERK2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127011BDBM50127011(CHEBI:35053 | Zoxazolamine)
Affinity DataKd:  9.40E+5nMAssay Description:Binding affinity to ERK2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)