Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50046708
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127174(CHEMBL3628599)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127173(CHEMBL3628598)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127164(CHEMBL3628597)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127160(CHEMBL3628595)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127204(CHEMBL3628602)
Affinity DataIC50: 108nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127203(CHEMBL3628601)
Affinity DataIC50: 116nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127206(CHEMBL3628604)
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127158(CHEMBL3628593)
Affinity DataIC50: 167nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127175(CHEMBL3628600)
Affinity DataIC50: 176nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127161(CHEMBL3628596)
Affinity DataIC50: 181nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127205(CHEMBL3628603)
Affinity DataIC50: 209nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127159(CHEMBL3628594)
Affinity DataIC50: 312nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: 561nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127164(CHEMBL3628597)
Affinity DataIC50: 602nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127174(CHEMBL3628599)
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127135(CHEMBL3628551)
Affinity DataIC50: 711nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127135(CHEMBL3628551)
Affinity DataIC50: 767nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127155(CHEMBL3628554)
Affinity DataIC50: 768nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: 809nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127206(CHEMBL3628604)
Affinity DataIC50: 922nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127173(CHEMBL3628598)
Affinity DataIC50: 936nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127160(CHEMBL3628595)
Affinity DataIC50: 977nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127203(CHEMBL3628601)
Affinity DataIC50: 982nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127139(CHEMBL3628553)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127175(CHEMBL3628600)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127158(CHEMBL3628593)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127156(CHEMBL3628555)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127205(CHEMBL3628603)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM70489(SMR000115594 | 3-[(3-methylphenyl)methyl]benzo[f]b...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127139(CHEMBL3628553)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127161(CHEMBL3628596)
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127204(CHEMBL3628602)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127159(CHEMBL3628594)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127137(CHEMBL3628552)
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127155(CHEMBL3628554)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM70489(SMR000115594 | 3-[(3-methylphenyl)methyl]benzo[f]b...)
Affinity DataIC50: 4.61E+3nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127157(CHEMBL3628556)
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127137(CHEMBL3628552)
Affinity DataIC50: 7.38E+3nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127174(CHEMBL3628599)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3 (unknown origin) expressed in Sf9 insect cells for 4 hrs by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3 (unknown origin) expressed in Sf9 insect cells for 4 hrs by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127174(CHEMBL3628599)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 125I-SDF-1 from human CXCR4 expressed in HEK293 cells incubated for 1.5 hrs by Topcount analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 125I-SDF-1 from human CXCR4 expressed in HEK293 cells incubated for 1.5 hrs by Topcount analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetCatalase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of catalase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127174(CHEMBL3628599)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127156(CHEMBL3628555)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetCatalase(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127174(CHEMBL3628599)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of catalase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127157(CHEMBL3628556)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127174(CHEMBL3628599)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PTP1B preincubated with protein for 15 mins followed by DiFMUP addition for 1 hr measured by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127135(CHEMBL3628551)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PTP1B preincubated with protein for 15 mins followed by DiFMUP addition for 1 hr measured by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
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