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Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50046721
TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127711(CHEMBL3629719)
Affinity DataIC50:  16nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127710(CHEMBL3629720)
Affinity DataIC50:  26nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127718(CHEMBL3629713)
Affinity DataIC50:  65nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127711(CHEMBL3629719)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127712(CHEMBL3629718)
Affinity DataIC50:  140nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127710(CHEMBL3629720)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127720(CHEMBL3629711)
Affinity DataIC50:  220nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127716(CHEMBL3629715)
Affinity DataIC50:  240nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127718(CHEMBL3629713)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127723(CHEMBL3629708)
Affinity DataIC50:  310nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127722(CHEMBL3629709)
Affinity DataIC50:  310nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127750(CHEMBL3629705)
Affinity DataIC50:  450nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127752(CHEMBL3629703)
Affinity DataIC50:  510nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127750(CHEMBL3629705)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127720(CHEMBL3629711)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127751(CHEMBL3629704)
Affinity DataIC50:  810nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127722(CHEMBL3629709)
Affinity DataIC50:  880nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127716(CHEMBL3629715)
Affinity DataIC50:  900nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127752(CHEMBL3629703)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127753(CHEMBL3629702)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127712(CHEMBL3629718)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127723(CHEMBL3629708)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127721(CHEMBL3629710)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127719(CHEMBL3629712)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127713(CHEMBL3629717)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127753(CHEMBL3629702)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127751(CHEMBL3629704)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127719(CHEMBL3629712)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127721(CHEMBL3629710)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127717(CHEMBL3629714)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127713(CHEMBL3629717)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127717(CHEMBL3629714)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127714(CHEMBL3629716)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127714(CHEMBL3629716)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127724(CHEMBL3629707)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127725(CHEMBL3629706)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127714(CHEMBL3629716)
Affinity DataIC50: >1.70E+4nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127714(CHEMBL3629716)
Affinity DataIC50: >1.70E+4nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127725(CHEMBL3629706)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human ACC2 expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetyl-CoA carboxylase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50127724(CHEMBL3629707)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of rat liver ACC1 preincubated for 10 mins followed by acetyl-CoA/KHCO3/[14C]-NaHCO3/ATP addition measured after 20 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed