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Found 8 Enz. Inhib. hit(s) with all data for entry = 50046727
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  190nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128343(CHEMBL3629176)
Affinity DataIC50:  560nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128344(CHEMBL3629177)
Affinity DataIC50:  580nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128342(CHEMBL3629175)
Affinity DataIC50:  1.31E+3nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128342(CHEMBL3629175)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128343(CHEMBL3629176)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128344(CHEMBL3629177)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50: >2.00E+4nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed