Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50046854
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135228BDBM50135228(CHEMBL3746729)
Affinity DataIC50: 70nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006805BDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134243BDBM50134243(CHEMBL3746644)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134251BDBM50134251(CHEMBL3746332)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134244BDBM50134244(CHEMBL3746705)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134249BDBM50134249(CHEMBL3746507)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134245BDBM50134245(CHEMBL3746542)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134250BDBM50134250(CHEMBL3746498)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134242BDBM50134242(CHEMBL3747740)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135226BDBM50135226(CHEMBL3747473)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135230BDBM50135230(CHEMBL3747438)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed