Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50046860
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134434BDBM50134434(CHEMBL3746046)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134433BDBM50134433(CHEMBL3745968)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134429BDBM50134429(CHEMBL3746964)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134432BDBM50134432(CHEMBL3747036)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134428BDBM50134428(CHEMBL3746007)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134393BDBM50134393(CHEMBL3746464)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134430BDBM50134430(CHEMBL3747248)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134434BDBM50134434(CHEMBL3746046)
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134431BDBM50134431(CHEMBL3747181)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134394BDBM50134394(CHEMBL3747325)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134391BDBM50134391(CHEMBL3747090)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134433BDBM50134433(CHEMBL3745968)
Affinity DataIC50: 8nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134389BDBM50134389(CHEMBL3747338)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134390BDBM50134390(CHEMBL3747602)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134392BDBM50134392(CHEMBL3747423)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134429BDBM50134429(CHEMBL3746964)
Affinity DataIC50: 130nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134386BDBM50134386(CHEMBL3747655)
Affinity DataIC50: 165nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134393BDBM50134393(CHEMBL3746464)
Affinity DataIC50: 243nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134430BDBM50134430(CHEMBL3747248)
Affinity DataIC50: 270nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134432BDBM50134432(CHEMBL3747036)
Affinity DataIC50: 480nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134431BDBM50134431(CHEMBL3747181)
Affinity DataIC50: 507nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134428BDBM50134428(CHEMBL3746007)
Affinity DataIC50: 629nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134391BDBM50134391(CHEMBL3747090)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134390BDBM50134390(CHEMBL3747602)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134387BDBM50134387(CHEMBL3747623)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134392BDBM50134392(CHEMBL3747423)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134394BDBM50134394(CHEMBL3747325)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134387BDBM50134387(CHEMBL3747623)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134388BDBM50134388(CHEMBL3747039)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134386BDBM50134386(CHEMBL3747655)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134386BDBM50134386(CHEMBL3747655)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE3 by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134389BDBM50134389(CHEMBL3747338)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134388BDBM50134388(CHEMBL3747039)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed