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Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50047047
TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145648(LP-778902 | LX1032 | LX1606 | Telotristat | Xermel...)
Affinity DataIC50:  16nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145634(CHEMBL3764999)
Affinity DataIC50:  26nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145635(CHEMBL3764206)
Affinity DataIC50:  50nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145636(CHEMBL3764034)
Affinity DataIC50:  55nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145672(CHEMBL3763889)
Affinity DataIC50:  65nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145673(CHEMBL3765147)
Affinity DataIC50:  79nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145637(CHEMBL3765301)
Affinity DataIC50:  96nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145649(CHEMBL3764908)
Affinity DataIC50:  128nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145638(CHEMBL3765770)
Affinity DataIC50:  211nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145650(CHEMBL3765094)
Affinity DataIC50:  211nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145639(CHEMBL3764448)
Affinity DataIC50:  361nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145640(CHEMBL3764208)
Affinity DataIC50:  449nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145641(CHEMBL3765608)
Affinity DataIC50:  519nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145651(CHEMBL3764555)
Affinity DataIC50:  583nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145647(CHEMBL3764524)
Affinity DataIC50:  871nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145642(CHEMBL3764344)
Affinity DataIC50:  949nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145643(CHEMBL3764387)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145644(CHEMBL3763222)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145645(CHEMBL3763343)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145646(CHEMBL3763702)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145658(CHEMBL3764570)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145659(CHEMBL3765042)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145660(CHEMBL3763485)
Affinity DataIC50:  2.15E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145652(CHEMBL3763909)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145662(CHEMBL3765662)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145653(CHEMBL3764091)
Affinity DataIC50:  2.96E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145654(CHEMBL3763347)
Affinity DataIC50:  3.42E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145663(CHEMBL3764874)
Affinity DataIC50:  4.04E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145664(CHEMBL3765403)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145665(CHEMBL3764099)
Affinity DataIC50:  5.26E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145655(CHEMBL3763681)
Affinity DataIC50:  5.93E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145666(CHEMBL3764358)
Affinity DataIC50:  6.22E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145667(CHEMBL3763726)
Affinity DataIC50:  7.55E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145668(CHEMBL3763372)
Affinity DataIC50:  8.54E+3nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145671(CHEMBL3764568)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145656(CHEMBL3764128)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145669(CHEMBL3763846)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTryptophan 5-hydroxylase 1(Human)
Karos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145657(CHEBI:47069 | CHEMBL412813)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TPH1 (unknown origin) using L-tyrosine as substrate after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed