Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50047584
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50384998(XANTHOHUMOL | CVD-0019905)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50384998(XANTHOHUMOL | CVD-0019905)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177002(CHEMBL3814590)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177000(CHEMBL3814665)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM19460(CHEMBL376915 | YS04 | (2S)-5,7-dihydroxy-2-(4-hydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177003(CHEMBL3813911)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177000(CHEMBL3814665)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177001(Xanthohumol C)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177001(Xanthohumol C)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50177002(CHEMBL3814590)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM19460(CHEMBL376915 | YS04 | (2S)-5,7-dihydroxy-2-(4-hydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed