Compile Data Set for Download or QSAR
Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 50013218
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056698BDBM50056698(CHEMBL3326930)
Affinity DataEC50:  1.13E+3nMAssay Description:Agonist activity at at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563770BDBM50563770(CHEMBL4786081)
Affinity DataEC50:  1.36E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563754BDBM50563754(CHEMBL4779978)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563748BDBM50563748(CHEMBL4798812)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563749BDBM50563749(CHEMBL4798699)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563766BDBM50563766(CHEMBL4784621)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563750BDBM50563750(CHEMBL4788239)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563767BDBM50563767(CHEMBL4783001)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563763BDBM50563763(CHEMBL4784184)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563777BDBM50563777(CHEMBL4786035)
Affinity DataEC50:  1.64E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563753BDBM50563753(CHEMBL4785005)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563771BDBM50563771(CHEMBL4800009)
Affinity DataEC50:  1.93E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563775BDBM50563775(CHEMBL4789165)
Affinity DataEC50:  1.96E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563778BDBM50563778(CHEMBL4795355)
Affinity DataEC50:  1.98E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563746BDBM50563746(CHEMBL4786921)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563776BDBM50563776(CHEMBL4781072)
Affinity DataEC50:  2.01E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563764BDBM50563764(CHEMBL4792768)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563773BDBM50563773(CHEMBL4791268)
Affinity DataEC50:  2.35E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR2 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as inhibition of Pam2CS-induced N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 3(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR3 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR4 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of LPS-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 5(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR5 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of flag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR7 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of imid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR9 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of ODN2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563743BDBM50563743(CHEMBL4783434)
Affinity DataEC50:  2.48E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563779BDBM50563779(CHEMBL4787815)
Affinity DataEC50:  2.48E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563744BDBM50563744(CHEMBL4780126)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563745BDBM50563745(CHEMBL4787710)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563747BDBM50563747(CHEMBL4794924)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563751BDBM50563751(CHEMBL4782254)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563768BDBM50563768(CHEMBL4784841)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563774BDBM50563774(CHEMBL4780573)
Affinity DataEC50:  2.57E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563752BDBM50563752(CHEMBL4777073)
Affinity DataEC50:  2.70E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563765BDBM50563765(CHEMBL4776983)
Affinity DataEC50:  2.94E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1alpha using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1B(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1beta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric ho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1delta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1G(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1gamma using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2alpha using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2beta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric ho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2delta using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2gamma using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK4 using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric hotspo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563769BDBM50563769(CHEMBL4781234)
Affinity DataEC50:  3.08E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563761BDBM50563761(CHEMBL4787810)
Affinity DataEC50:  4.04E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563757BDBM50563757(CHEMBL4794560)
Affinity DataEC50:  5.10E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 6.72E+3nMAssay Description:Inhibition of TLR8 in human CD14-positive monocytes cells in presence of TLR7 stimulusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563772BDBM50563772(CHEMBL4784330)
Affinity DataEC50:  6.83E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563780BDBM50563780(CHEMBL4795714)
Affinity DataIC50: 7.46E+3nMAssay Description:Inhibition of TLR8 in human CD14-positive monocytes cells in presence of TLR4 stimulusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50563759BDBM50563759(CHEMBL4777656)
Affinity DataEC50:  8.00E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
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