Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50022528
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC3/NcoR2 using Boc-Lys-(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human C-terminal His/FLAG-tagged HDAC1 using Boc-Lys-(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 184nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged HDAC2 using Boc-Lys-(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50254780(CHEMBL4078477 | US10301323, Compound D2 | US990889...)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC3/NcoR2 using Boc-Lys-(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC8 using Boc-Lys-(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50254780(CHEMBL4078477 | US10301323, Compound D2 | US990889...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of recombinant human C-terminal His/FLAG-tagged HDAC1 using Boc-Lys-(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50254780(CHEMBL4078477 | US10301323, Compound D2 | US990889...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged HDAC2 using Boc-Lys-(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50254780(CHEMBL4078477 | US10301323, Compound D2 | US990889...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC8 using Boc-Lys-(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed