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Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50047348
TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161472(CHEMBL3785095)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161467(CHEMBL3785560)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161471(CHEMBL3785718)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161400(CHEMBL3785952)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161399(CHEMBL3786469)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161474(CHEMBL3787174)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161475(CHEMBL3785605)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161402(CHEMBL3786899)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161473(CHEMBL3785728)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161476(CHEMBL3785839)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161403(CHEMBL3786338)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161405(CHEMBL3787051)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161475(CHEMBL3785605)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161403(CHEMBL3786338)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161467(CHEMBL3785560)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161405(CHEMBL3787051)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161476(CHEMBL3785839)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161472(CHEMBL3785095)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161402(CHEMBL3786899)
Affinity DataKi:  225nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161404(CHEMBL3786486)
Affinity DataKi:  231nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161404(CHEMBL3786486)
Affinity DataKi: >250nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161401(CHEMBL3786946)
Affinity DataKi: >250nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161471(CHEMBL3785718)
Affinity DataKi:  288nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161474(CHEMBL3787174)
Affinity DataKi:  289nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161399(CHEMBL3786469)
Affinity DataKi:  342nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161473(CHEMBL3785728)
Affinity DataKi:  392nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161401(CHEMBL3786946)
Affinity DataKi: >450nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161400(CHEMBL3785952)
Affinity DataKi: >450nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161467(CHEMBL3785560)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161400(CHEMBL3785952)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161472(CHEMBL3785095)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161471(CHEMBL3785718)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161399(CHEMBL3786469)
Affinity DataIC50:  59nMAssay Description:Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161475(CHEMBL3785605)
Affinity DataIC50:  122nMAssay Description:Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50161399(CHEMBL3786469)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161473(CHEMBL3785728)
Affinity DataIC50:  227nMAssay Description:Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161402(CHEMBL3786899)
Affinity DataIC50:  248nMAssay Description:Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50161473(CHEMBL3785728)
Affinity DataIC50:  340nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50161405(CHEMBL3787051)
Affinity DataIC50:  500nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50161474(CHEMBL3787174)
Affinity DataIC50:  683nMAssay Description:Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50161471(CHEMBL3785718)
Affinity DataIC50:  940nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50161400(CHEMBL3785952)
Affinity DataIC50:  970nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50161472(CHEMBL3785095)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50161402(CHEMBL3786899)
Affinity DataIC50: >1.50E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50161475(CHEMBL3785605)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50161467(CHEMBL3785560)
Affinity DataIC50:  1.73E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50161404(CHEMBL3786486)
Affinity DataIC50:  6.96E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed