Compile Data Set for Download or QSAR
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Report error Found 84 Enz. Inhib. hit(s) with all data for entry = 50047503
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  0.0250nMAssay Description:Competitive binding affinity to EGFR (unknown origin) ATP binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171877(CHEMBL3806248 | US10106508, Compound I-34)
Affinity DataIC50:  2nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171909(CHEMBL3805859 | US10106508, Compound I-39)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171879(CHEMBL3805774 | US10106508, Compound I-36)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171880(CHEMBL3804868 | US10106508, Compound I-37)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171877(CHEMBL3806248 | US10106508, Compound I-34)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171911(CHEMBL3805461 | US10106508, Compound I-31)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171878(CHEMBL3805039 | US10106508, Compound I-35)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171908(CHEMBL3805238 | US10106508, Compound I-38)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171910(CHEMBL3806110 | US10106508, Compound I-30)
Affinity DataIC50:  11nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50172007(CHEMBL3805236 | US10106508, Compound I-28)
Affinity DataIC50:  11nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171910(CHEMBL3806110 | US10106508, Compound I-30)
Affinity DataIC50:  13nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171918(CHEMBL3806170 | US10106508, Compound I-24)
Affinity DataIC50:  17nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50172009(CHEMBL3806143)
Affinity DataIC50:  18nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171911(CHEMBL3805461 | US10106508, Compound I-31)
Affinity DataIC50:  21nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171919(CHEMBL3805782)
Affinity DataIC50:  21nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171878(CHEMBL3805039 | US10106508, Compound I-35)
Affinity DataIC50:  22nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50172010(CHEMBL3805681)
Affinity DataIC50:  22nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  23nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50172008(CHEMBL3806292 | US10106508, Compound I-29)
Affinity DataIC50:  23nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171969(CHEMBL3806213 | US10106508, Compound I-40)
Affinity DataIC50:  24nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171960(CHEMBL3805509 | US10106508, Compound I-8)
Affinity DataIC50:  24nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50172055(CHEMBL3805218)
Affinity DataIC50:  26nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171968(CHEMBL3805325 | US10106508, Compound I-41)
Affinity DataIC50:  27nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171961(CHEMBL3805283 | US10106508, Compound I-7)
Affinity DataIC50:  29nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171960(CHEMBL3805509 | US10106508, Compound I-8)
Affinity DataIC50:  31nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171880(CHEMBL3804868 | US10106508, Compound I-37)
Affinity DataIC50:  34nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171917(CHEMBL3806200 | US10106508, Compound I-12)
Affinity DataIC50:  36nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171915(CHEMBL3805333 | US10106508, Compound I-10)
Affinity DataIC50:  44nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171961(CHEMBL3805283 | US10106508, Compound I-7)
Affinity DataIC50:  46nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50172056(CHEMBL3806145 | US10106508, Compound I-21)
Affinity DataIC50:  58nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50172057(CHEMBL3806222)
Affinity DataIC50:  59nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171879(CHEMBL3805774 | US10106508, Compound I-36)
Affinity DataIC50:  70nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171908(CHEMBL3805238 | US10106508, Compound I-38)
Affinity DataIC50:  71nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171916(CHEMBL3805299 | US10106508, Compound I-11)
Affinity DataIC50:  75nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171950(CHEMBL3805584 | US10106508, Compound I-26)
Affinity DataIC50:  76nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171966(CHEMBL3805383 | US10106508, Compound I-2)
Affinity DataIC50:  83nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50172011(CHEMBL3804886)
Affinity DataIC50:  84nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171954(CHEMBL3805775 | US10106508, Compound I-25)
Affinity DataIC50:  89nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50172012(CHEMBL3805588)
Affinity DataIC50:  97nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171964(CHEMBL3805177 | US10106508, Compound I-4)
Affinity DataIC50:  103nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171913(CHEMBL3806066 | US10106508, Compound I-33)
Affinity DataIC50:  109nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171968(CHEMBL3805325 | US10106508, Compound I-41)
Affinity DataIC50:  121nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171909(CHEMBL3805859 | US10106508, Compound I-39)
Affinity DataIC50:  124nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171919(CHEMBL3805782)
Affinity DataIC50:  151nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171913(CHEMBL3806066 | US10106508, Compound I-33)
Affinity DataIC50:  160nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171965(CHEMBL3805089 | US10106508, Compound I-3)
Affinity DataIC50:  185nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171912(CHEMBL3806005 | US10106508, Compound I-32)
Affinity DataIC50:  200nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50171958(CHEMBL3806172 | US10106508, Compound I-16)
Affinity DataIC50:  232nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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