Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50001782
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50016425(3-{2-[2-(2-{2-[2-(tert-Butoxycarbonyl-methyl-amino...)
Affinity DataKi:  0.230nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataKi:  0.280nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataKi:  0.280nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018060(CHEMBL264273 | Boc-cyclo-(gama-D-Glu-Tyr(SO3H)-Nle...)
Affinity DataKi:  0.560nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50016425(3-{2-[2-(2-{2-[2-(tert-Butoxycarbonyl-methyl-amino...)
Affinity DataKi:  0.930nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018066(CHEMBL437661 | Boc-cyclo-(gama-D-Glu-Tyr-Nle-D-Lys...)
Affinity DataKi:  4.70nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018064(CHEMBL2370588 | Boc-cyclo-(Asp-Tyr(SO3H)-Nle-D-Lys...)
Affinity DataKi:  6.40nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018067(CHEMBL267329 | Boc-cyclo-(D-Glu-Tyr(SO3H)-Nle-D-Ly...)
Affinity DataKi:  9.10nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018063(CHEMBL384731 | Boc-cyclo-(D-Glu-Tyr-Nle-D-Lys)-Trp...)
Affinity DataKi:  28nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018062(CHEMBL266990 | Boc-cyclo-(Glu-Tyr(SO3H)-Nle-D-Lys)...)
Affinity DataKi:  29nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018068(CHEMBL273880 | Boc-cyclo-(Glu-Tyr-Nle-D-Lys)-Trp-N...)
Affinity DataKi:  47nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018057(CHEMBL216831 | Boc-D-Glu-Tyr(SO3H)-Nle-D-Nle-Trp-N...)
Affinity DataKi:  54nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018058(CHEMBL2370598 | Boc-cyclo-(D-Asp-Tyr(SO3H)-Nle-D-L...)
Affinity DataKi:  120nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018069(CHEMBL384618 | Boc-gama-D-Glu-Tyr(SO3H)-Nle-D-Lys-...)
Affinity DataKi:  301nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018065(CHEMBL440259 | Boc-D-Glu-Tyr(SO3H)-Nle-D-Lys-Trp-N...)
Affinity DataKi:  313nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018061(CHEMBL386304 | Boc-Glu-Tyr(SO3H)-Nle-D-Lys-Trp-Nle...)
Affinity DataKi:  334nMAssay Description:Ability to displace specific binding of 0.2 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018063(CHEMBL384731 | Boc-cyclo-(D-Glu-Tyr-Nle-D-Lys)-Trp...)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018069(CHEMBL384618 | Boc-gama-D-Glu-Tyr(SO3H)-Nle-D-Lys-...)
Affinity DataKi:  1.39E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018058(CHEMBL2370598 | Boc-cyclo-(D-Asp-Tyr(SO3H)-Nle-D-L...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018065(CHEMBL440259 | Boc-D-Glu-Tyr(SO3H)-Nle-D-Lys-Trp-N...)
Affinity DataKi:  1.55E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018057(CHEMBL216831 | Boc-D-Glu-Tyr(SO3H)-Nle-D-Nle-Trp-N...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018066(CHEMBL437661 | Boc-cyclo-(gama-D-Glu-Tyr-Nle-D-Lys...)
Affinity DataKi:  1.89E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018061(CHEMBL386304 | Boc-Glu-Tyr(SO3H)-Nle-D-Lys-Trp-Nle...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018068(CHEMBL273880 | Boc-cyclo-(Glu-Tyr-Nle-D-Lys)-Trp-N...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of 0.1 nM [3H]pCCK-8 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018060(CHEMBL264273 | Boc-cyclo-(gama-D-Glu-Tyr(SO3H)-Nle...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018064(CHEMBL2370588 | Boc-cyclo-(Asp-Tyr(SO3H)-Nle-D-Lys...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018067(CHEMBL267329 | Boc-cyclo-(D-Glu-Tyr(SO3H)-Nle-D-Ly...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50018062(CHEMBL266990 | Boc-cyclo-(Glu-Tyr(SO3H)-Nle-D-Lys)...)
Affinity DataKi:  3.85E+3nMAssay Description:Displacement of 0.1 nM [3H]Boc[Nle28,31]-CCK27-33 from guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed