Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50047800
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13934BDBM13934(CGP 73547 | CHEMBL1163 | methyl N-[(1S)-1-{[(2S,3S...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190623BDBM50190623(CHEMBL3828743)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190638BDBM50190638(CHEMBL3828119)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190624BDBM50190624(CHEMBL3828417)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190625BDBM50190625(CHEMBL3828552)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190631BDBM50190631(CHEMBL3828166)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190639BDBM50190639(CHEMBL3827524)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190629BDBM50190629(CHEMBL3828678)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190636BDBM50190636(CHEMBL3828275)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190641BDBM50190641(CHEMBL3827205)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190640BDBM50190640(CHEMBL3828355)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190642BDBM50190642(CHEMBL3827353)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190627BDBM50190627(CHEMBL3827958)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190626BDBM50190626(CHEMBL3827319)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190637BDBM50190637(CHEMBL3827348)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190628BDBM50190628(CHEMBL3827975)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190632BDBM50190632(CHEMBL3827450)
Affinity DataIC50: 12nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190630BDBM50190630(CHEMBL3827960)
Affinity DataIC50: 14nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190633BDBM50190633(CHEMBL3827407)
Affinity DataIC50: 20nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190634BDBM50190634(CHEMBL3828494)
Affinity DataIC50: 27nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190635BDBM50190635(CHEMBL3827668)
Affinity DataIC50: 37nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed