Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50009948
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50374441(CHEMBL429848)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50384416(CHEMBL291536 | CHEMBL2111553 | SB-334867)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533697(CHEMBL4531556)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533697(CHEMBL4531556)
Affinity DataKi:  100nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533697(CHEMBL4531556)
Affinity DataKi:  100nMAssay Description:Antagonist activity at human OX2 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533702(CHEMBL4578783)
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533702(CHEMBL4578783)
Affinity DataKi:  200nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533702(CHEMBL4578783)
Affinity DataKi:  300nMAssay Description:Antagonist activity at human OX2 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533701(CHEMBL4548914)
Affinity DataIC50: 300nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533701(CHEMBL4548914)
Affinity DataKi:  400nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533695(CHEMBL1481561)
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533703(CHEMBL4473709)
Affinity DataIC50: 700nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533700(CHEMBL4471376)
Affinity DataIC50: 700nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533696(CHEMBL4544095)
Affinity DataIC50: 800nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533700(CHEMBL4471376)
Affinity DataKi:  800nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533695(CHEMBL1481561)
Affinity DataKi:  800nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533695(CHEMBL1481561)
Affinity DataKi:  900nMAssay Description:Antagonist activity at human OX2 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50167073(CHEMBL3798017)
Affinity DataIC50: 900nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533703(CHEMBL4473709)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533700(CHEMBL4471376)
Affinity DataKi:  1.00E+3nMAssay Description:Antagonist activity at human OX2 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533701(CHEMBL4548914)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533700(CHEMBL4471376)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533702(CHEMBL4578783)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533703(CHEMBL4473709)
Affinity DataKi:  1.20E+3nMAssay Description:Antagonist activity at human OX2 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50167073(CHEMBL3798017)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533696(CHEMBL4544095)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50167073(CHEMBL3798017)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533700(CHEMBL4471376)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533699(CHEMBL4475736)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533696(CHEMBL4544095)
Affinity DataKi:  1.70E+3nMAssay Description:Antagonist activity at human OX2 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533701(CHEMBL4548914)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533702(CHEMBL4578783)
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50167073(CHEMBL3798017)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533699(CHEMBL4475736)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533696(CHEMBL4544095)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533696(CHEMBL4544095)
Affinity DataIC50: 4.80E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533702(CHEMBL4578783)
Affinity DataKi:  6.00E+3nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533697(CHEMBL4531556)
Affinity DataKi:  6.30E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533695(CHEMBL1481561)
Affinity DataKi:  6.70E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533700(CHEMBL4471376)
Affinity DataKi:  7.00E+3nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533698(CHEMBL4445194)
Affinity DataKi:  7.60E+3nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533696(CHEMBL4544095)
Affinity DataKi:  1.03E+4nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533701(CHEMBL4548914)
Affinity DataKi:  1.10E+4nMAssay Description:Antagonist activity at human OX2 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533697(CHEMBL4531556)
Affinity DataIC50: 1.11E+4nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533695(CHEMBL1481561)
Affinity DataIC50: 1.17E+4nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533698(CHEMBL4445194)
Affinity DataIC50: 1.18E+4nMAssay Description:Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533703(CHEMBL4473709)
Affinity DataKi:  1.20E+4nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533695(CHEMBL1481561)
Affinity DataKi:  1.31E+4nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533698(CHEMBL4445194)
Affinity DataIC50: 1.33E+4nMAssay Description:Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50533701(CHEMBL4548914)
Affinity DataKi:  1.62E+4nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cell membranes assessed as inhibition of orexin A-induced Ca2+ elevation after 30 mins in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
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