Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50048150
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175305BDBM50175305(CHEMBL3600873)
Affinity DataIC50: 0.0460nMAssay Description:Inhibition of human recombinant His-tagged Aurora A expressed in Escherichia coli using RRR(GLRRASLG)4R-NH2 as substrate after 40 mins in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206389BDBM50206389(CHEMBL3939307)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206389BDBM50206389(CHEMBL3939307)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206389BDBM50206389(CHEMBL3939307)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004205BDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of recombinant N-terminal His6-tagged Aurora A (1 to 403 residues) (unknown origin) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase C(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004205BDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of recombinant N-terminal His6-tagged Aurora C (1 to 309 residues) (unknown origin) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase C(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175305BDBM50175305(CHEMBL3600873)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged Aurora C (1 to 275 end residues) expressed in baculovirus expression system using G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175305BDBM50175305(CHEMBL3600873)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged Aurora B (1 to 344 end residues) expressed in baculovirus expression system coexpre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206412BDBM50206412(CHEMBL3986609)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004205BDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataKi:  18nMAssay Description:Inhibition of recombinant N-terminal His6-tagged Aurora B (62 to 344 residues) (unknown origin) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206412BDBM50206412(CHEMBL3986609)
Affinity DataIC50: 26nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206393BDBM50206393(CHEMBL3954695)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206406BDBM50206406(CHEMBL3975342)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206409BDBM50206409(CHEMBL3983327)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206391BDBM50206391(CHEMBL3894492)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206413BDBM50206413(CHEMBL3974375)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206408BDBM50206408(CHEMBL3939365)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206415BDBM50206415(CHEMBL3923159)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206407BDBM50206407(CHEMBL3946005)
Affinity DataIC50: 51nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206409BDBM50206409(CHEMBL3983327)
Affinity DataIC50: 60nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206392BDBM50206392(CHEMBL3922175)
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206415BDBM50206415(CHEMBL3923159)
Affinity DataIC50: 66nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206406BDBM50206406(CHEMBL3975342)
Affinity DataIC50: 74nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206408BDBM50206408(CHEMBL3939365)
Affinity DataIC50: 83nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206416BDBM50206416(CHEMBL3953964)
Affinity DataIC50: 85nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206392BDBM50206392(CHEMBL3922175)
Affinity DataIC50: 208nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206414BDBM50206414(CHEMBL3935219)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206419BDBM50206419(CHEMBL3901797)
Affinity DataIC50: 260nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206446BDBM50206446(CHEMBL3912937)
Affinity DataIC50: 260nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206413BDBM50206413(CHEMBL3974375)
Affinity DataIC50: 310nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206414BDBM50206414(CHEMBL3935219)
Affinity DataIC50: 314nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206391BDBM50206391(CHEMBL3894492)
Affinity DataIC50: 480nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206393BDBM50206393(CHEMBL3954695)
Affinity DataIC50: 480nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206418BDBM50206418(CHEMBL3961791)
Affinity DataIC50: 790nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206410BDBM50206410(CHEMBL3929110)
Affinity DataIC50: 790nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206390BDBM50206390(CHEMBL3909328)
Affinity DataIC50: 950nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206416BDBM50206416(CHEMBL3953964)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206447BDBM50206447(CHEMBL3946537)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206417BDBM50206417(CHEMBL3964280)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206444BDBM50206444(CHEMBL3901151)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206411BDBM50206411(CHEMBL3901743)
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206445BDBM50206445(CHEMBL3972822)
Affinity DataIC50: 9.61E+3nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206394BDBM50206394(CHEMBL3970521)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed