Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 7422
TargetBromodomain-containing protein 4 [44-168](Human)
China Pharmaceutical University

LigandPNGBDBM193890((R)-4-benzyl-6-(3,5-dimethylisoxazol-4-yl)-3-ethyl...)
Affinity DataIC50: 73nMT: 2°CAssay Description:11 compounds were evaluated against BRD4-BD1 in vitro with compound 28a as the reference compound. BRD4 (44-168 aa) was bought from Active Motif. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
China Pharmaceutical University

LigandPNGBDBM193884(1(R)-4-benzyl-6-(3,5-dimethylisoxazol-4-yl)-3-meth...)
Affinity DataIC50: 75nMT: 2°CAssay Description:11 compounds were evaluated against BRD4-BD1 in vitro with compound 28a as the reference compound. BRD4 (44-168 aa) was bought from Active Motif. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
China Pharmaceutical University

LigandPNGBDBM193891((R)-3,4-dibenzyl-6-(3,5-dimethylisoxazol-4-yl)-3,4...)
Affinity DataIC50: 151nMT: 2°CAssay Description:11 compounds were evaluated against BRD4-BD1 in vitro with compound 28a as the reference compound. BRD4 (44-168 aa) was bought from Active Motif. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
China Pharmaceutical University

LigandPNGBDBM193885(2(R)-6-(3,5-dimethylisoxazol-4-yl)-4-(4-methoxyben...)
Affinity DataIC50: 160nMT: 2°CAssay Description:11 compounds were evaluated against BRD4-BD1 in vitro with compound 28a as the reference compound. BRD4 (44-168 aa) was bought from Active Motif. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
China Pharmaceutical University

LigandPNGBDBM193888((R)-6-(3,5-dimethylisoxazol-4-yl)-4-(4-methoxybenz...)
Affinity DataIC50: 220nMT: 2°CAssay Description:11 compounds were evaluated against BRD4-BD1 in vitro with compound 28a as the reference compound. BRD4 (44-168 aa) was bought from Active Motif. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
China Pharmaceutical University

LigandPNGBDBM60929(4(R)-4-cyclopentyl-6-(3,5-dimethylisoxazol-4-yl)-3...)
Affinity DataIC50: 370nMT: 2°CAssay Description:11 compounds were evaluated against BRD4-BD1 in vitro with compound 28a as the reference compound. BRD4 (44-168 aa) was bought from Active Motif. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
China Pharmaceutical University

LigandPNGBDBM193886(4(R)-4-cyclopentyl-6-(3,5-dimethylisoxazol-4-yl)-3...)
Affinity DataIC50: 440nMT: 2°CAssay Description:11 compounds were evaluated against BRD4-BD1 in vitro with compound 28a as the reference compound. BRD4 (44-168 aa) was bought from Active Motif. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
China Pharmaceutical University

LigandPNGBDBM193892(4-(4-Chlorobenzyl)-6-(3,5-dimethylisoxazol-4-yl)-3...)
Affinity DataIC50: 500nMT: 2°CAssay Description:11 compounds were evaluated against BRD4-BD1 in vitro with compound 28a as the reference compound. BRD4 (44-168 aa) was bought from Active Motif. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
China Pharmaceutical University

LigandPNGBDBM193889(8(R)-4-benzyl-6-(3,5-dimethylisoxazol-4-yl)-3-(hyd...)
Affinity DataIC50: 650nMT: 2°CAssay Description:11 compounds were evaluated against BRD4-BD1 in vitro with compound 28a as the reference compound. BRD4 (44-168 aa) was bought from Active Motif. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2016
Entry Details Article
PubMed