Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50047951
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM28661(GW501516 | CHEMBL38943 | 2-{2-methyl-4-[({4-methyl...)
Affinity DataEC50:  5.90nMAssay Description:Agonist activity at GAL4-tagged human PPARdelta ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50189627(N-{3-[4-(4-isopropoxyphenoxy)phenyl]-1-methylprop-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198340(CHEMBL3965346)
Affinity DataIC50: 16nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50099491(cid_3392731 | CHEMBL21241 | 2-(4-{2-[3-Cyclohexyl-...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at GAL4-tagged human PPARalpha ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198328(CHEMBL3911590)
Affinity DataIC50: 48nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198332(CHEMBL3901560)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198337(CHEMBL3905544)
Affinity DataEC50:  150nMAssay Description:Agonist activity at GAL4-tagged human PPARalpha ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198331(CHEMBL3901479)
Affinity DataEC50:  210nMAssay Description:Agonist activity at GAL4-tagged human PPARalpha ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198337(CHEMBL3905544)
Affinity DataIC50: 220nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataEC50:  260nMAssay Description:Agonist activity at GAL4-tagged human PPARgamma ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198339(CHEMBL3892532)
Affinity DataIC50: 260nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198337(CHEMBL3905544)
Affinity DataEC50:  290nMAssay Description:Agonist activity at GAL4-tagged human PPARdelta ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198329(CHEMBL3981588)
Affinity DataIC50: 290nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198329(CHEMBL3981588)
Affinity DataEC50:  320nMAssay Description:Agonist activity at GAL4-tagged human PPARdelta ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198329(CHEMBL3981588)
Affinity DataEC50:  320nMAssay Description:Agonist activity at GAL4-tagged human PPARalpha ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198333(CHEMBL3920527)
Affinity DataEC50:  330nMAssay Description:Agonist activity at GAL4-tagged human PPARalpha ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198333(CHEMBL3920527)
Affinity DataEC50:  370nMAssay Description:Agonist activity at GAL4-tagged human PPARdelta ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198331(CHEMBL3901479)
Affinity DataEC50:  390nMAssay Description:Agonist activity at GAL4-tagged human PPARdelta ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198333(CHEMBL3920527)
Affinity DataIC50: 420nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198335(CHEMBL3939357)
Affinity DataIC50: 610nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198330(CHEMBL3957862)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at GAL4-tagged human PPARalpha ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198330(CHEMBL3957862)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at GAL4-tagged human PPARdelta ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198334(CHEMBL3930369)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50198336(CHEMBL3941344)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of full length recombinant C-terminal His-tagged human ACC2 expressed in baculovirus infected sf9 cells using acetyl-CoA as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed