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Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 50047833
LigandPNGBDBM50192809(CHEMBL3941914)
Affinity DataIC50:  0.220nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50192811(CHEMBL3971502)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192807(CHEMBL3984947)
Affinity DataIC50:  0.360nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192809(CHEMBL3941914)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of hypotonicity-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50192804(CHEMBL3933401)
Affinity DataIC50:  0.570nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192820(CHEMBL3950646)
Affinity DataIC50:  0.900nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192808(CHEMBL3915150)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192779(CHEMBL3957347)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192817(CHEMBL3924485)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192781(CHEMBL3985107)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192827(CHEMBL3985405)
Affinity DataIC50:  1.90nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192826(CHEMBL3979114)
Affinity DataIC50:  2.10nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192809(CHEMBL3941914)
Affinity DataIC50:  2.10nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of hypotonicity-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50192803(CHEMBL3906685)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192819(CHEMBL3908777)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192822(CHEMBL3897222)
Affinity DataIC50:  2.90nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192778(CHEMBL3942384)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192776(CHEMBL3979627)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192816(CHEMBL3968344)
Affinity DataIC50:  4.40nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192828(CHEMBL3914089)
Affinity DataIC50:  4.5nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192824(CHEMBL3924665)
Affinity DataIC50:  4.80nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192774(CHEMBL3986034)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192813(CHEMBL3896628)
Affinity DataIC50:  6.20nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192777(CHEMBL3915675)
Affinity DataIC50:  6.70nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192825(CHEMBL3976867)
Affinity DataIC50:  8.40nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192809(CHEMBL3941914)
Affinity DataIC50:  8.60nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50192804(CHEMBL3933401)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192811(CHEMBL3971502)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192807(CHEMBL3984947)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192815(CHEMBL3906180)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192820(CHEMBL3950646)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192802(CHEMBL3927993)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192810(CHEMBL3942090)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192779(CHEMBL3957347)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192775(CHEMBL3915493)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192772(CHEMBL3967702)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192806(CHEMBL3960867)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192780(CHEMBL3977334)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192817(CHEMBL3924485)
Affinity DataIC50:  53nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192822(CHEMBL3897222)
Affinity DataIC50:  57nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192821(CHEMBL2133556)
Affinity DataIC50:  57nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50192828(CHEMBL3914089)
Affinity DataIC50:  57nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192814(CHEMBL3933578)
Affinity DataIC50:  80nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192778(CHEMBL3942384)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192824(CHEMBL3924665)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192813(CHEMBL3896628)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192777(CHEMBL3915675)
Affinity DataIC50:  290nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192802(CHEMBL3927993)
Affinity DataIC50:  360nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50192776(CHEMBL3979627)
Affinity DataIC50:  410nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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