Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50047888
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195700BDBM50195700(CHEMBL3975893)
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195694BDBM50195694(CHEMBL3976876)
Affinity DataIC50: 5.90nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195690BDBM50195690(CHEMBL3917128)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195693BDBM50195693(CHEMBL3947597)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195778BDBM50195778(CHEMBL3971582)
Affinity DataIC50: 71nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373831BDBM50373831(CHEMBL272087)
Affinity DataIC50: 89nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195691BDBM50195691(CHEMBL3986868)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195546BDBM50195546(CHEMBL3956307)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195776BDBM50195776(CHEMBL3932828)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195701BDBM50195701(CHEMBL3956293)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195779BDBM50195779(CHEMBL3984953)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195695BDBM50195695(CHEMBL3941037)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195773BDBM50195773(CHEMBL3901754)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195689BDBM50195689(CHEMBL3959223)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195552BDBM50195552(CHEMBL3944344)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195772BDBM50195772(CHEMBL3896148)
Affinity DataIC50: 230nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195620BDBM50195620(CHEMBL3930834)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195558BDBM50195558(CHEMBL3890162)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195771BDBM50195771(CHEMBL3950523)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195563BDBM50195563(CHEMBL3913038)
Affinity DataIC50: 680nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195700BDBM50195700(CHEMBL3975893)
Affinity DataIC50: 790nMAssay Description:Inhibition of LPA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195571BDBM50195571(CHEMBL3973793)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195565BDBM50195565(CHEMBL3972833)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195692BDBM50195692(CHEMBL3905099)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195581BDBM50195581(CHEMBL3915800)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195607BDBM50195607(CHEMBL3902849)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195548BDBM50195548(CHEMBL3912909)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195688BDBM50195688(CHEMBL3979511)
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195775BDBM50195775(CHEMBL3903904)
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195547BDBM50195547(CHEMBL3921894)
Affinity DataIC50: 5.50E+3nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195774BDBM50195774(CHEMBL3953068)
Affinity DataIC50: 6.60E+3nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195695BDBM50195695(CHEMBL3941037)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of LPA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195695BDBM50195695(CHEMBL3941037)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LPA3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195573BDBM50195573(CHEMBL3981813)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195546BDBM50195546(CHEMBL3956307)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LPA3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195700BDBM50195700(CHEMBL3975893)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LPA3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195579BDBM50195579(CHEMBL3959003)
Affinity DataIC50: 1.21E+4nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50195546BDBM50195546(CHEMBL3956307)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of LPA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed