Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50022531
TargetEpithelial discoidin domain-containing receptor 1(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandPNGBDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to DDR1 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor Tie-1(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandPNGBDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataKd:  0.900nMAssay Description:Binding affinity to TIE1 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandPNGBDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to DDR2 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandPNGBDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of TIE2 autophosphorylation in human HUVEC cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandPNGBDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to TIE2 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 10(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandPNGBDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataKd:  5.90nMAssay Description:Binding affinity to LOK (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandPNGBDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed