Compile Data Set for Download or QSAR
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Found 16 Enz. Inhib. hit(s) with all data for entry = 50048070
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203455(CHEMBL3906151)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203453(CHEMBL3947880)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203450(CHEMBL3916184)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203454(CHEMBL3961612)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203456(CHEMBL3987007)
Affinity DataIC50:  11nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203457(CHEMBL3985315)
Affinity DataIC50:  12nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203451(CHEMBL3943036)
Affinity DataIC50:  18nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203446(CHEMBL3952889)
Affinity DataIC50:  19nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203449(CHEMBL3925190)
Affinity DataIC50:  21nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203447(CHEMBL3913553)
Affinity DataIC50:  27nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203452(CHEMBL3972633)
Affinity DataIC50:  108nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203458(CHEMBL3915551)
Affinity DataIC50:  138nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)
Affinity DataIC50:  180nMAssay Description:Inhibition of CCDC6/RET (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203448(CHEMBL3961567)
Affinity DataIC50:  342nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoiled-coil domain-containing protein 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203455(CHEMBL3906151)
Affinity DataIC50:  407nMAssay Description:Inhibition of CCDC6/RET (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed