Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50048079
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204014BDBM50204014(CHEMBL3944424 | US10059667, Example 27)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells coexpressing NFAT BLA assessed as increase in intracellular Ca2+ flux by fluo-4-AM dye based F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204018BDBM50204018(CHEMBL3923877)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at rat GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102727BDBM50102727(CHEMBL3330550)
Affinity DataEC50:  6nMAssay Description:Agonist activity at GPR40 (unknown origin) by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204015BDBM50204015(CHEMBL3954235)
Affinity DataEC50:  10nMAssay Description:Agonist activity at GPR40 (unknown origin) by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204016BDBM50204016(CHEMBL3959220)
Affinity DataEC50: <10nMAssay Description:Agonist activity at human GPR40 expressed in CHOK cells assessed as increase in intracellular Ca2+ flux by Fluo-4 based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204019BDBM50204019(CHEMBL3927863)
Affinity DataEC50:  10nMAssay Description:Agonist activity at rat GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204021BDBM50204021(CHEMBL3931755)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells coexpressing NFAT BLA assessed as increase in intracellular Ca2+ flux by fluo-4-AM dye based F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362690BDBM50362690(CHEMBL1829173 | AMG-837)
Affinity DataEC50:  13nMAssay Description:Agonist activity at GPR40 (unknown origin) by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204023BDBM50204023(CHEMBL3905856)
Affinity DataEC50:  42nMAssay Description:Agonist activity at flag-tagged human GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204024BDBM50204024(CHEMBL3973075)
Affinity DataEC50:  71nMAssay Description:Agonist activity at flag-tagged human GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204017BDBM50204017(CHEMBL3966288)
Affinity DataEC50: <100nMAssay Description:Agonist activity at full length recombinant human GPR40 expressed in CHOK1 cells assessed as intracellular IP3 accumulation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204020BDBM50204020(CHEMBL3927519)
Affinity DataEC50:  119nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by calcium-4 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204011BDBM50204011(CHEMBL3958983)
Affinity DataEC50:  146nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by calcium-4 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204012BDBM50204012(CHEMBL3955132)
Affinity DataEC50:  152nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by calcium-4 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50200369BDBM50200369(CHEMBL3915620)
Affinity DataEC50:  233nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by calcium-4 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204010BDBM50204010(CHEMBL3928769)
Affinity DataEC50: <300nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells coexpressing NFAT BLA assessed as increase in intracellular Ca2+ flux by fluo-4-AM dye based F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204013BDBM50204013(CHEMBL3900797)
Affinity DataEC50:  380nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells coexpressing NFAT BLA assessed as increase in intracellular Ca2+ flux by fluo-4-AM dye based F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Rat)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204022BDBM50204022(CHEMBL3954105)
Affinity DataEC50:  630nMAssay Description:Agonist activity at rat GPR40 expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2018
Entry Details Article
PubMed