Compile Data Set for Download or QSAR
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Found 9 Enz. Inhib. hit(s) with all data for entry = 50049154
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50235322(CHEMBL4066593)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM9009(7-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity was determined against bovine liver beta galactosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50235323(CHEMBL4080023)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50235324(CHEMBL4104258)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM9006(6-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-hexanoic ...)
Affinity DataIC50:  1nMAssay Description:Inhibition of bovine erythrocyte AchE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50133473(CHEMBL3632994)
Affinity DataIC50:  54nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50133473(CHEMBL3632994)
Affinity DataIC50:  80nMAssay Description:Inhibition of Ache (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50235325(CHEMBL4060617)
Affinity DataIC50:  253nMAssay Description:Inhibition of human AchE-induced amyloid beta (1 to 40) aggregation after 48 hrs by thioflavin T fluorescence spectroscopic methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Tehran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50235326(CHEBI:51240 | Propidium | Propidium Iodide | Propi...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of human AchE-induced amyloid beta (1 to 40) aggregation after 48 hrs by thioflavin T fluorescence spectroscopic methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed