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Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50047937
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50189884(CHEMBL3827618)
Affinity DataKi:  7nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197835(CHEMBL3965905)
Affinity DataKi:  7nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197827(CHEMBL3894507)
Affinity DataKi:  7nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197843(CHEMBL3941236)
Affinity DataKi:  9nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197841(CHEMBL3932068)
Affinity DataKi:  9nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197832(CHEMBL3913249)
Affinity DataKi:  11nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197831(CHEMBL3949996)
Affinity DataKi:  13nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197865(CHEMBL3938843)
Affinity DataKi:  15nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197837(CHEMBL3911402)
Affinity DataKi:  17nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197864(CHEMBL3923116)
Affinity DataKi:  21nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360232(CHEMBL1928186)
Affinity DataKi:  24nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360236(CHEMBL1928172)
Affinity DataKi:  26nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197842(CHEMBL3922253)
Affinity DataKi:  36nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197830(CHEMBL3962753)
Affinity DataKi:  44nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197846(CHEMBL3954708)
Affinity DataKi:  47nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197861(CHEMBL3895144)
Affinity DataKi:  50nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197833(CHEMBL3974385)
Affinity DataKi:  63nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197845(CHEMBL3904245)
Affinity DataKi:  64nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197863(CHEMBL3968387)
Affinity DataKi:  86nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197839(CHEMBL3964826)
Affinity DataKi:  97nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197828(CHEMBL3904073)
Affinity DataKi:  132nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197862(CHEMBL3932242)
Affinity DataKi:  135nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197840(CHEMBL3914131)
Affinity DataKi:  190nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197836(CHEMBL3946020)
Affinity DataKi:  190nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197823(CHEMBL3975350)
Affinity DataKi:  221nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360234(CHEMBL1928188)
Affinity DataKi:  245nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197822(CHEMBL3924502)
Affinity DataKi:  405nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197824(CHEMBL3983947)
Affinity DataKi:  407nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197825(CHEMBL1928057)
Affinity DataKi:  467nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197826(CHEMBL3923295)
Affinity DataKi:  796nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197844(CHEMBL3975921)
Affinity DataKi:  1.54E+3nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360227(CHEMBL1928180)
Affinity DataIC50:  40nMAssay Description:Inhibition of purified human placental microsomal 17beta-HSD2 using [3H]-E2 substrate and NAD+ by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360232(CHEMBL1928186)
Affinity DataIC50:  100nMAssay Description:Inhibition of purified human placental microsomal 17beta-HSD2 using [3H]-E2 substrate and NAD+ by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360234(CHEMBL1928188)
Affinity DataIC50:  260nMAssay Description:Inhibition of purified human placental microsomal 17beta-HSD2 using [3H]-E2 substrate and NAD+ by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360231(CHEMBL1928185)
Affinity DataIC50:  260nMAssay Description:Inhibition of purified human placental microsomal 17beta-HSD2 using [3H]-E2 substrate and NAD+ by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360227(CHEMBL1928180)
Affinity DataIC50:  290nMAssay Description:Inhibition of purified human placental cytosolic 17beta-HSD1 using [3H]-E1 substrate and NADH by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360232(CHEMBL1928186)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of purified human placental cytosolic 17beta-HSD1 using [3H]-E1 substrate and NADH by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360231(CHEMBL1928185)
Affinity DataIC50:  5.48E+3nMAssay Description:Inhibition of purified human placental cytosolic 17beta-HSD1 using [3H]-E1 substrate and NADH by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360234(CHEMBL1928188)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of purified human placental cytosolic 17beta-HSD1 using [3H]-E1 substrate and NADH by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed