Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50047937
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50189884BDBM50189884(CHEMBL3827618)
Affinity DataKi:  7nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197835BDBM50197835(CHEMBL3965905)
Affinity DataKi:  7nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197827BDBM50197827(CHEMBL3894507)
Affinity DataKi:  7nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197841BDBM50197841(CHEMBL3932068)
Affinity DataKi:  9nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197843BDBM50197843(CHEMBL3941236)
Affinity DataKi:  9nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197832BDBM50197832(CHEMBL3913249)
Affinity DataKi:  11nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197831BDBM50197831(CHEMBL3949996)
Affinity DataKi:  13nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197865BDBM50197865(CHEMBL3938843)
Affinity DataKi:  15nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197837BDBM50197837(CHEMBL3911402)
Affinity DataKi:  17nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197864BDBM50197864(CHEMBL3923116)
Affinity DataKi:  21nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360232BDBM50360232(CHEMBL1928186)
Affinity DataKi:  24nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360236BDBM50360236(CHEMBL1928172)
Affinity DataKi:  26nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197842BDBM50197842(CHEMBL3922253)
Affinity DataKi:  36nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360227BDBM50360227(CHEMBL1928180)
Affinity DataIC50: 40nMAssay Description:Inhibition of purified human placental microsomal 17beta-HSD2 using [3H]-E2 substrate and NAD+ by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197830BDBM50197830(CHEMBL3962753)
Affinity DataKi:  44nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197846BDBM50197846(CHEMBL3954708)
Affinity DataKi:  47nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197861BDBM50197861(CHEMBL3895144)
Affinity DataKi:  50nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197833BDBM50197833(CHEMBL3974385)
Affinity DataKi:  63nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197845BDBM50197845(CHEMBL3904245)
Affinity DataKi:  64nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197863BDBM50197863(CHEMBL3968387)
Affinity DataKi:  86nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197839BDBM50197839(CHEMBL3964826)
Affinity DataKi:  97nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360232BDBM50360232(CHEMBL1928186)
Affinity DataIC50: 100nMAssay Description:Inhibition of purified human placental microsomal 17beta-HSD2 using [3H]-E2 substrate and NAD+ by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197828BDBM50197828(CHEMBL3904073)
Affinity DataKi:  132nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197862BDBM50197862(CHEMBL3932242)
Affinity DataKi:  135nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197836BDBM50197836(CHEMBL3946020)
Affinity DataKi:  190nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197840BDBM50197840(CHEMBL3914131)
Affinity DataKi:  190nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197823BDBM50197823(CHEMBL3975350)
Affinity DataKi:  221nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360234BDBM50360234(CHEMBL1928188)
Affinity DataKi:  245nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360234BDBM50360234(CHEMBL1928188)
Affinity DataIC50: 260nMAssay Description:Inhibition of purified human placental microsomal 17beta-HSD2 using [3H]-E2 substrate and NAD+ by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360231BDBM50360231(CHEMBL1928185)
Affinity DataIC50: 260nMAssay Description:Inhibition of purified human placental microsomal 17beta-HSD2 using [3H]-E2 substrate and NAD+ by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360227BDBM50360227(CHEMBL1928180)
Affinity DataIC50: 290nMAssay Description:Inhibition of purified human placental cytosolic 17beta-HSD1 using [3H]-E1 substrate and NADH by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197822BDBM50197822(CHEMBL3924502)
Affinity DataKi:  405nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197824BDBM50197824(CHEMBL3983947)
Affinity DataKi:  407nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197825BDBM50197825(CHEMBL1928057)
Affinity DataKi:  467nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197826BDBM50197826(CHEMBL3923295)
Affinity DataKi:  796nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360232BDBM50360232(CHEMBL1928186)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of purified human placental cytosolic 17beta-HSD1 using [3H]-E1 substrate and NADH by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase 14(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197844BDBM50197844(CHEMBL3975921)
Affinity DataKi:  1.54E+3nMAssay Description:Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360231BDBM50360231(CHEMBL1928185)
Affinity DataIC50: 5.48E+3nMAssay Description:Inhibition of purified human placental cytosolic 17beta-HSD1 using [3H]-E1 substrate and NADH by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Philipps University Marburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360234BDBM50360234(CHEMBL1928188)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of purified human placental cytosolic 17beta-HSD1 using [3H]-E1 substrate and NADH by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2018
Entry Details Article
PubMed