Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50048282
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211284BDBM50211284(CHEMBL3959435)
Affinity DataIC50: 5.70E+3nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211284BDBM50211284(CHEMBL3959435)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211282BDBM50211282(CHEMBL308493)
Affinity DataIC50: 7.60E+3nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211280BDBM50211280(S007-1558 (S))
Affinity DataIC50: 9.00E+3nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82258BDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 1.04E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82258BDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211282BDBM50211282(CHEMBL308493)
Affinity DataIC50: 1.61E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211280BDBM50211280(S007-1558 (S))
Affinity DataIC50: 2.53E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016900BDBM50016900(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
Affinity DataIC50: 3.50E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-induced platelet aggregation preincubated for 60 sec ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016900BDBM50016900(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
Affinity DataIC50: 4.00E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211282BDBM50211282(CHEMBL308493)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211287BDBM50211287(CHEMBL3957185)
Affinity DataKd:  5.20E+4nMAssay Description:Binding affinity to GP6 receptor (unknown origin) by NMR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211284BDBM50211284(CHEMBL3959435)
Affinity DataIC50: 5.35E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211285BDBM50211285(CHEMBL3948507)
Affinity DataKd:  5.70E+4nMAssay Description:Binding affinity to GP6 receptor (unknown origin) by NMR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211283BDBM50211283(CHEMBL2263356)
Affinity DataIC50: 8.68E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211283BDBM50211283(CHEMBL2263356)
Affinity DataIC50: 1.26E+5nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82258BDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 1.58E+5nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211280BDBM50211280(S007-1558 (S))
Affinity DataIC50: 1.81E+5nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211283BDBM50211283(CHEMBL2263356)
Affinity DataIC50: 5.00E+5nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetPlatelet glycoprotein VI(Human)
Academy of Scientific and Innovative Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211281BDBM50211281(CHEMBL3894250)
Affinity DataKd:  8.50E+5nMAssay Description:Binding affinity to GP6 receptor (unknown origin) by NMR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed