Compile Data Set for Download or QSAR
Report error Found 123 Enz. Inhib. hit(s) with all data for entry = 50011728
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550438BDBM50550438(CHEMBL4798388)
Affinity DataIC50: 90nMAssay Description:Inhibition of active recombinant human N-terminal His-tagged 11-betaHSD1 expressed in Escherichia coli using cortisone, NADPH and glucose-6-phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550442BDBM50550442(CHEMBL4747862)
Affinity DataIC50: 230nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550438BDBM50550438(CHEMBL4798388)
Affinity DataIC50: 270nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550441BDBM50550441(CHEMBL4790846)
Affinity DataIC50: 270nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550438BDBM50550438(CHEMBL4798388)
Affinity DataIC50: 470nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550483BDBM50550483(CHEMBL4751940)
Affinity DataIC50: 690nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550477BDBM50550477(CHEMBL4796479)
Affinity DataIC50: 810nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550443BDBM50550443(CHEMBL4747823)
Affinity DataIC50: 860nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550472BDBM50550472(CHEMBL4779399)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550471BDBM50550471(CHEMBL4763449)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550385BDBM50550385(CHEMBL4753084)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550385BDBM50550385(CHEMBL4753084)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550438BDBM50550438(CHEMBL4798388)
Affinity DataIC50: 1.90E+3nMAssay Description:Allosteric inhibition of Myc-tagged IDH1 R132H mutant (unknown origin) expressed in human THP-1 cells assessed as inhibition of 2-HG production incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550383BDBM50550383(CHEMBL4760640)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550484BDBM50550484(CHEMBL4754505)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550438BDBM50550438(CHEMBL4798388)
Affinity DataIC50: 2.30E+3nMAssay Description:Allosteric inhibition of IDH1 R132H mutant (unknown origin) expressed in HEK293T cells assessed as reduction in 2-HG production incubated for 48 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550482BDBM50550482(CHEMBL4785487)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550383BDBM50550383(CHEMBL4760640)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550444BDBM50550444(CHEMBL4759241)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550384BDBM50550384(CHEMBL4748734)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550446BDBM50550446(CHEMBL4749350)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550384BDBM50550384(CHEMBL4748734)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550474BDBM50550474(CHEMBL4778659)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550445BDBM50550445(CHEMBL4795545)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550481BDBM50550481(CHEMBL4758089)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550448BDBM50550448(CHEMBL4759317)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550473BDBM50550473(CHEMBL4754955)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550450BDBM50550450(CHEMBL4753540)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550447BDBM50550447(CHEMBL4745793)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550449BDBM50550449(CHEMBL4797648)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550480BDBM50550480(CHEMBL4743661)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550412BDBM50550412(CHEMBL4764671)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550451BDBM50550451(CHEMBL4760471)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550413BDBM50550413(CHEMBL4764584)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550454BDBM50550454(CHEMBL4758453)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550453BDBM50550453(CHEMBL4751611)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550458BDBM50550458(CHEMBL4781537)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550469BDBM50550469(CHEMBL4752193)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550452BDBM50550452(CHEMBL4750921)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550418BDBM50550418(CHEMBL4797659)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550456BDBM50550456(CHEMBL4741078)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550427BDBM50550427(CHEMBL4755116)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550425BDBM50550425(CHEMBL4786122)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550457BDBM50550457(CHEMBL4791653)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550459BDBM50550459(CHEMBL4781442)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550460BDBM50550460(CHEMBL4748430)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 119225BDBM119225(US8673938, 136)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550461BDBM50550461(CHEMBL4742140)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550462BDBM50550462(CHEMBL4760275)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550421BDBM50550421(CHEMBL4776196)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
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