Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50049187
TargetGlycogen synthase kinase-3 beta(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant rat N-terminal GST-tagged GSK3beta expressed in Escherichia coli assessed as reduction in tau phosphorylation preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of tau (unknown origin) fibril formation by thioflavin-T fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMed
TargetMicrotubule-associated protein tau(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of tau (unknown origin) fibril formation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2019
Entry Details Article
PubMed