Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50048996
LigandChemical structure of BindingDB Monomer ID 50232621BDBM50232621(CHEMBL4093284)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232631BDBM50232631(CHEMBL4104464)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232627BDBM50232627(CHEMBL4098051)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232631BDBM50232631(CHEMBL4104464)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232622BDBM50232622(CHEMBL4060838)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232629BDBM50232629(CHEMBL4077033)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232621BDBM50232621(CHEMBL4093284)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232622BDBM50232622(CHEMBL4060838)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232625BDBM50232625(CHEMBL4080222)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232627BDBM50232627(CHEMBL4098051)
Affinity DataEC50:  0.840nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232626BDBM50232626(CHEMBL4070965)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232632BDBM50232632(CHEMBL4083676)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232624BDBM50232624(CHEMBL4099186)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232629BDBM50232629(CHEMBL4077033)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232632BDBM50232632(CHEMBL4083676)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232628BDBM50232628(CHEMBL4097638)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232624BDBM50232624(CHEMBL4099186)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232626BDBM50232626(CHEMBL4070965)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232630BDBM50232630(CHEMBL4062339)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232623BDBM50232623(CHEMBL4081159)
Affinity DataEC50:  5.10nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232630BDBM50232630(CHEMBL4062339)
Affinity DataEC50:  6.60nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232628BDBM50232628(CHEMBL4097638)
Affinity DataEC50:  6.70nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232625BDBM50232625(CHEMBL4080222)
Affinity DataEC50:  6.70nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232623BDBM50232623(CHEMBL4081159)
Affinity DataEC50:  9.40nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232633BDBM50232633(CHEMBL4089040)
Affinity DataEC50:  16nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase in intracellular cAMP level after 60 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232633BDBM50232633(CHEMBL4089040)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232623BDBM50232623(CHEMBL4081159)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232627BDBM50232627(CHEMBL4098051)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232626BDBM50232626(CHEMBL4070965)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232631BDBM50232631(CHEMBL4104464)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232624BDBM50232624(CHEMBL4099186)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232625BDBM50232625(CHEMBL4080222)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232628BDBM50232628(CHEMBL4097638)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232622BDBM50232622(CHEMBL4060838)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232630BDBM50232630(CHEMBL4062339)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human ERG by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232621BDBM50232621(CHEMBL4093284)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232621BDBM50232621(CHEMBL4093284)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human ERG by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232629BDBM50232629(CHEMBL4077033)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232630BDBM50232630(CHEMBL4062339)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232621BDBM50232621(CHEMBL4093284)
Affinity DataEC50: >3.00E+4nMAssay Description:Activity at human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232621BDBM50232621(CHEMBL4093284)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50232632BDBM50232632(CHEMBL4083676)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed