Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 50049204
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236453(CHEMBL4068323)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibitory activity against beta-glucosidase of sweet almondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236447(CHEMBL4069817)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236444(CHEMBL4090812)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236441(CHEMBL4072541)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236456(CHEMBL4081995)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236457(CHEMBL4074211)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236451(CHEMBL4080514)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236468(CHEMBL4061143)
Affinity DataIC50:  56nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236459(CHEMBL4100964)
Affinity DataIC50:  64nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236469(CHEMBL4083022)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236470(CHEMBL4099458)
Affinity DataIC50:  66nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236467(CHEMBL4073106)
Affinity DataIC50:  75nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236452(CHEMBL4098535)
Affinity DataIC50:  86nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236443(CHEMBL4082148)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236460(CHEMBL4084510)
Affinity DataIC50:  121nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236461(CHEMBL4062833)
Affinity DataIC50:  124nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236462(CHEMBL4091932)
Affinity DataIC50:  149nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236366(CHEMBL4083038)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236445(CHEMBL4097729)
Affinity DataIC50:  177nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236499(CHEMBL4085481)
Affinity DataIC50:  209nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236453(CHEMBL4068323)
Affinity DataIC50:  310nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236446(CHEMBL4070580)
Affinity DataIC50:  336nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236506(CHEMBL4082560)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236365(CHEMBL4090002)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236508(CHEMBL4060684)
Affinity DataIC50:  451nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236501(CHEMBL4090396)
Affinity DataIC50:  618nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236505(CHEMBL4069361)
Affinity DataIC50:  674nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236502(CHEMBL4063458)
Affinity DataIC50:  804nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236454(CHEMBL4105450)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236507(CHEMBL4091316)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236448(CHEMBL4101114)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236449(CHEMBL4074371)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236450(CHEMBL4092252)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236510(CHEMBL4071459)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236442(CHEMBL4061953)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236500(CHEMBL4100005)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236464(CHEMBL4072081)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of [3H]5-HT uptake at striatal nerve endings by serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236386(CHEMBL4069834)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236385(CHEMBL4085095)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 2(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236444(CHEMBL4090812)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 2(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of KDM1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236360(CHEMBL4066708)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetLysine-specific histone demethylase 2(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236441(CHEMBL4072541)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of KDM1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 2(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236447(CHEMBL4069817)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of KDM1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] A(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236441(CHEMBL4072541)
Affinity DataIC50:  2.49E+4nMAssay Description:Inhibition of recombinant human MAOA incubated for 15 mins measured after 30 mins by luminescence-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236398(CHEMBL1503273)
Affinity DataIC50:  2.57E+4nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236399(CHEMBL4082564)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] A(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50236444(CHEMBL4090812)
Affinity DataIC50:  4.13E+4nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] A(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)
Affinity DataIC50:  4.13E+4nMAssay Description:Inhibition of recombinant human MAOA incubated for 15 mins measured after 30 mins by luminescence-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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