Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50049170
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5447BDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235600BDBM50235600(CHEMBL3542268)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235601BDBM50235601(CHEMBL4089347)
Affinity DataIC50: 16nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235598BDBM50235598(CHEMBL4066845)
Affinity DataIC50: 24nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5445BDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Key Laboratory of The Ministry of Education For Medicinal Resources and Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235599BDBM50235599(CHEMBL4088135)
Affinity DataIC50: 34nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed