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Found 30 Enz. Inhib. hit(s) with all data for entry = 50000927
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264655(CHEMBL4102571)
Affinity DataIC50:  170nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264683(CHEMBL4081699)
Affinity DataIC50:  300nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264652(CHEMBL4079599)
Affinity DataIC50:  360nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264682(CHEMBL4059766)
Affinity DataIC50:  390nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264654(CHEMBL4067388)
Affinity DataIC50:  400nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264682(CHEMBL4059766)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264685(CHEMBL4078305)
Affinity DataIC50:  760nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264686(CHEMBL4093947)
Affinity DataIC50:  850nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264684(CHEMBL4080691)
Affinity DataIC50:  890nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264652(CHEMBL4079599)
Affinity DataIC50:  890nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264686(CHEMBL4093947)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264687(CHEMBL4076207)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264683(CHEMBL4081699)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264655(CHEMBL4102571)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264687(CHEMBL4076207)
Affinity DataIC50:  3.04E+3nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264684(CHEMBL4080691)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264654(CHEMBL4067388)
Affinity DataIC50:  4.99E+3nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264657(CHEMBL4086191)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264685(CHEMBL4078305)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264653(CHEMBL4094833)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264688(CHEMBL4071149)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264653(CHEMBL4094833)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264688(CHEMBL4071149)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264681(CHEMBL4073273)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264656(CHEMBL4064686)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264657(CHEMBL4086191)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264656(CHEMBL4064686)
Affinity DataIC50:  8.20E+4nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50264681(CHEMBL4073273)
Affinity DataIC50:  9.70E+4nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed