Compile Data Set for Download or QSAR
Report error Found 119 Enz. Inhib. hit(s) with all data for entry = 50049209
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144508BDBM50144508(4-Methyl-1-(5-phenyl-pentyl)-piperidine | CHEMBL30...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236721BDBM50236721(CHEMBL4073530)
Affinity DataKi:  0.0800nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236715BDBM50236715(CHEMBL4067210)
Affinity DataKi:  0.130nMAssay Description:Displacement of [125I]DOI from rat cortex 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236730BDBM50236730(CHEMBL4072342)
Affinity DataKi:  0.140nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064708BDBM50064708((R)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041246BDBM50041246(Methyl-phenethyl-(5-phenyl-pentyl)-amine | CHEMBL1...)
Affinity DataKi:  0.25nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041275BDBM50041275(Methyl-(5-phenyl-pentyl)-propyl-amine | CHEMBL2034...)
Affinity DataKi:  0.290nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156192BDBM50156192((1R,2R)-2-(4-Bromo-2,5-dimethoxy-phenyl)-2-methoxy...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041251BDBM50041251(1-(5-Phenyl-pentyl)-piperidine | CHEMBL20188)
Affinity DataKi:  0.380nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041237BDBM50041237(((R)-1-Methyl-2-phenyl-ethyl)-(5-phenyl-pentyl)-am...)
Affinity DataKi:  0.5nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156193BDBM50156193((1R,2R)-2-Amino-1-(4-bromo-2,5-dimethoxy-phenyl)-p...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005257BDBM50005257(2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylami...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [125I]DOI from recombinant human 5HT2A expressed in Syrian hamster AV12 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28582BDBM28582([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]DOB from 5HT2A in Sprague-Dawley rat cortex membranes measured after 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28582BDBM28582([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]DOI from recombinant human 5HT2A expressed in Syrian hamster AV12 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156185BDBM50156185((1S,2R)-2-(4-Bromo-2,5-dimethoxy-phenyl)-2-methoxy...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005257BDBM50005257(2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylami...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]DOB from 5HT2A in Sprague-Dawley rat cortex membranes measured after 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041266BDBM50041266(((S)-1-Methyl-2-phenyl-ethyl)-(5-phenyl-pentyl)-am...)
Affinity DataKi:  0.900nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156189BDBM50156189((1R,2S)-2-Amino-1-(4-bromo-2,5-dimethoxy-phenyl)-p...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21393BDBM21393(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21395BDBM21395(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat frontal cortex membranes measured after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016737BDBM50016737(CHEMBL11760 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50395860BDBM50395860(CHEMBL2165520)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016743BDBM50016743(CHEMBL285351 | 7-(3-Phenyl-propylamino)-5,6,7,8-te...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156188BDBM50156188(2-(4-Bromo-2,5-dimethoxy-phenyl)-2-methoxy-ethylam...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016740BDBM50016740(CHEMBL27937 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016745BDBM50016745(CHEMBL28111 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34141BDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156191BDBM50156191(2-Amino-1-(4-bromo-2,5-dimethoxy-phenyl)-ethanol |...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236727BDBM50236727(CHEMBL4088891)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of DAT in Sprague-Dawley rat synaptosomes assessed as reduction in [3H]dopamine uptake by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016736BDBM50016736(CHEMBL27019 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21395BDBM21395(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]DOI-HCL from 5HT2A in Sprague-Dawley rat frontal cortex membranes measured after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236723BDBM50236723(CHEMBL4064950)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016738BDBM50016738(CHEMBL27609 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016777BDBM50016777(7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley rat cortex membranes after 15 mins by liquid scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016744BDBM50016744(CHEMBL27252 | (8-Methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156195BDBM50156195((1S,2S)-2-(4-Bromo-2,5-dimethoxy-phenyl)-2-methoxy...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091067BDBM50091067(2-[2-Methoxy-4-(3-phenyl-propyl)-phenyl]-1-methyl-...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]ketanserin from rat 5HT2A expressed in mouse NIH/3T3 cell membranes after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156196BDBM50156196((1S,2R)-2-Amino-1-(4-bromo-2,5-dimethoxy-phenyl)-p...)
Affinity DataKi:  9.20nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50016771BDBM50016771(CHEMBL164814 | 7-Diethylamino-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  9.70nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley rat cortex membranes after 15 mins by liquid scintillation spectrometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156187BDBM50156187((1S,2S)-2-Amino-1-(4-bromo-2,5-dimethoxy-phenyl)-p...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10755BDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DOI-HCL from 5HT2A in Sprague-Dawley rat frontal cortex membranes measured after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 86285BDBM86285(NSC_1576 | CAS_1576 | Methcathinone, (-))
Affinity DataEC50:  13nMAssay Description:Activity at DAT (unknown origin) assessed as release of [3H]DAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104815BDBM50104815(2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-1-methyl-...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]ketanserin from rat 5HT2A expressed in mouse NIH/3T3 cell membranes after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236724BDBM50236724(CHEMBL4084187)
Affinity DataEC50:  15nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091076BDBM50091076(2-[3-Methoxy-4-(3-phenyl-propyl)-phenyl]-1-methyl-...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]ketanserin from rat 5HT2A expressed in mouse NIH/3T3 cell membranes after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156184BDBM50156184((1R,2S)-2-(4-Bromo-2,5-dimethoxy-phenyl)-2-methoxy...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I](+/-)DOI from rat 5HT2A after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28582BDBM28582([125I]2,5-dimethoxy-4-iodoamphetamine | DOI,(-) | ...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat cortex membranes measured after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025200BDBM50025200(CHEMBL3330645)
Affinity DataEC50:  20nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104818BDBM50104818(2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-ethylamin...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]ketanserin from rat 5HT2A expressed in mouse NIH/3T3 cell membranes after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193463BDBM50193463(N-(3-(2-aminoethyl)phenyl)benzenesulfonamide | CHE...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
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