Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50022616
TargetEpidermal growth factor receptor(Human)
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of EGFR C797S/T790M/L858R mutant (unknown origin) incubated for 10 mins in presence of ATP by ADP-Glo based luminometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 53nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 10 mins in presence of ATP by ADP-Glo based luminometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)